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Modeling Temperature-Sensitive Neural Networks in the Hypothalamus

Pirc, Alycia Ann

Abstract Details

2011, Master of Science, Ohio State University, Mathematics.
The idea of a set-point temperature for thermoregulatory control was hypothesized by H.T. Hammel in 1965. Warm-sensitive neurons and temperature insensitive neurons in the hypothalamus signal to synaptically driven effector neurons. Thermosensitivity is measured by a neuron’s firing rate, or the number of action potentials in a given time. The result of Hammel's work is a feed-forward neural network that influences the body’s control of heat production and heat loss. We extend his idea into a system of differential equations modeling the feed-forward neural network of his design. The results of our model focus on the firing rates of the effector neuron. Generally, our model agrees with the propositions posed by Hammel and his predecessors: effector neurons are synaptically driven to display characteristics of thermosensitive neurons.
Janet Best (Advisor)
Jack Boulant (Committee Member)

Recommended Citations

Citations

  • Pirc, A. A. (2011). Modeling Temperature-Sensitive Neural Networks in the Hypothalamus [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1306811701

    APA Style (7th edition)

  • Pirc, Alycia. Modeling Temperature-Sensitive Neural Networks in the Hypothalamus. 2011. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1306811701.

    MLA Style (8th edition)

  • Pirc, Alycia. "Modeling Temperature-Sensitive Neural Networks in the Hypothalamus." Master's thesis, Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1306811701

    Chicago Manual of Style (17th edition)