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A Biomechanical Study of Critical Size Cranial Defect Reconstruction Techniques Using Two Bone Substitutes

Porzel, Alec P.
http://rave.ohiolink.edu/etdc/view?acc_num=akron1208547531

Abstract Details

2008, Master of Science in Engineering, University of Akron, Biomedical Engineering.
When a skull graft is performed, a surgeon can leave the remaining defect cavity unfilled or fill it with bone cement.This research project studied cranial vault defect reconstructions immediately following surgical procedure using impact testing. This study, divided into three stages utilizing forty-two (42) fresh human cadaver specimens, addressed the clinical needs of a surgeon by evaluating three reconstruction techniques. Stage 1 compared the biomechanical characteristics of a partial thickness bone graft (n = 4) versus full thickness bone (n = 4). Stage 2 evaluated the biomechanical characteristics of a partial thickness graft filled with bone cement (n = 9) to those of an unfilled partial thickness bone graft (n = 9). Stage 3 compared the biomechanical characteristics of two bone substitutes, Stryker® HydroSet® Bone Substitute (n=6) and Norian® SRS® Fast Set Putty® (n = 6). Peak acceleration and energy absorption from initiation of impact to peak acceleration were the parameters used for analysis. In Stage 1, the parameter of peak acceleration showed a significant difference between full bone and the unfilled bone graft, full bone being favorable (p = 0.0311). The parameter of energy absorption did not show a significant difference (p = 0.1105) between the two techniques. However, the mean value of energy absorption of full bone (8.52 ± 3.88 Nm) was about two times that of partial bone (4.36 ± 2.40 Nm). In Stage 2, the parameter of peak acceleration showed a significant difference between an unfilled bone graft and a bone graft filled with Norian bone cement, the Norian sample being favorable (p = 0.0023). The parameter of energy absorption showed a significant difference in Norian's favor (p = 0.0109) between the two techniques. In Stage 3, the parameter of peak acceleration did not show a significant difference between a bone graft filled with Stryker HydroSet Bone Substitute and a bone graft filled with Norian SRS Fast Set Putty (p = 0.2343). Based on deviation from the means, Norian's performance was more predictable than Stryker's cement. The parameter of energy absorption did not show a significant difference (p = 0.5155) between the two techniques.
Glen Njus, PhD (Advisor)
Daniel Sheffer, PhD (Committee Member)
Stanley Rittgers, PhD (Committee Member)
110 p.
Biomedical Research; Engineering; Health Care
Cranial Vault; Bone Substitute; Reconstruction; Skull; Impact Testing

Recommended Citations

Citations

  • Porzel, A. P. (2008). A Biomechanical Study of Critical Size Cranial Defect Reconstruction Techniques Using Two Bone Substitutes [Master's thesis, University of Akron]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=akron1208547531

    APA Style (7th edition)

  • Porzel, Alec. A Biomechanical Study of Critical Size Cranial Defect Reconstruction Techniques Using Two Bone Substitutes. 2008. University of Akron, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=akron1208547531.

    MLA Style (8th edition)

  • Porzel, Alec. "A Biomechanical Study of Critical Size Cranial Defect Reconstruction Techniques Using Two Bone Substitutes." Master's thesis, University of Akron, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=akron1208547531

    Chicago Manual of Style (17th edition)

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© 2008, all rights reserved.
This open access ETD is published by University of Akron and OhioLINK.