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AFREH_Isaac_Masters Thesis -2013.pdf (1.72 MB)

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A Non-Biological Inhibition Based Sensing Technique (NIBS) for the Detection of Halogenated Disinfection By-Products in Water

Afreh, Isaac K
http://rave.ohiolink.edu/etdc/view?acc_num=akron1366068222

Abstract Details

2013, Master of Science, University of Akron, Chemical Engineering.
The purpose of this work is to apply a newly developed technique, non-biological inhibition based sensing (NIBS), for the detection of toxic halogenated disinfection by-products in water. NIBS is a chemical amplification method where the analyte of interest inhibits a given catalyzed reaction rather than enhancing the reaction rate. NIBS works similar to enzymatic inhibition except that NIBS does not use enzymes - which are very unstable and suffer short shelf-life - as catalyst. The NIBS chemistry is focused on the selective binding of colorimetric reactions. Although colorimetric methods are selective to certain classes of compounds, they are not particularly sensitive. NIBS allows for both selective and sensitive detection of catalyst inhibition, without the shelf-life issues associated with enzymatic detection methods. Previous work has shown that the NIBS technique can successfully lower the detection limit of sulfides and arsines in water samples, compared to standard colorimetric methods. The work presented here focuses on application of NIBS towards the detection of halogenated organic compounds with a specific focus on trihalomethanes (THMs). To achieve effective detection of halogenated organics, the effects of reaction temperature and reactant concentrations on the NIBS reaction were studied and optimized. In the present NIBS method, a pyridine-catalyzed reaction is inhibited due to the presence of THMs in water at parts-per-million (ppm) concentrations. In addition, the NIBS method is selective to THMs and a few other halogenated organics. These promising results demonstrate the further success of the NIBS technique for sensitive, selective detection. Future work will be carried out to incorporate the NIBS technique in sensing applications for THMs in drinking water.
Chelsea Monty, Dr. (Advisor)
Stephen Duirk, Dr. (Committee Member)
Zhenmeng Peng, Dr. (Committee Member)
105 p.
Chemical Engineering
Non-biological inhibition sensing; Disinfection by-product; Trihalomethanes; Open-circuit potential

Recommended Citations

Citations

  • Afreh, I. K. (2013). A Non-Biological Inhibition Based Sensing Technique (NIBS) for the Detection of Halogenated Disinfection By-Products in Water [Master's thesis, University of Akron]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=akron1366068222

    APA Style (7th edition)

  • Afreh, Isaac. A Non-Biological Inhibition Based Sensing Technique (NIBS) for the Detection of Halogenated Disinfection By-Products in Water. 2013. University of Akron, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=akron1366068222.

    MLA Style (8th edition)

  • Afreh, Isaac. "A Non-Biological Inhibition Based Sensing Technique (NIBS) for the Detection of Halogenated Disinfection By-Products in Water." Master's thesis, University of Akron, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=akron1366068222

    Chicago Manual of Style (17th edition)

akron1366068222
829
© 2013, all rights reserved.
This open access ETD is published by University of Akron and OhioLINK.