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Investigation of The Structure-Property Correlations of Pendent Functionalized Antimicrobial Polyurethanes

Abstract Details

2018, Master of Science, University of Akron, Polymer Science.
Antibiotics have been used to treat bacterial infections. However, bacteria would develop drug resistance that makes the drugs less effective with long-term treatment of traditional antibiotics. To address this situation, antimicrobial polymers that could significantly lower resistance formation have been developed as a promising alternative strategy for combating antimicrobial infections. Previously, our lab developed water-soluble peptidomimetic antimicrobial polyurethanes with cationic pendant groups that showed good antimicrobial activity against Gran negative bacteria, such E. coli, but were not effective against Gram positive bacteria such as S. aureus. In this work, modification of the described antimicrobial polymer with different hydrophobic moieties is presented with the aim to investigate the effect of structural change on the antimicrobial activity against Gram negative and Gram positive bacteria.
Abraham Joy (Advisor)
Yu Zhu (Committee Member)
44 p.

Recommended Citations

Citations

  • Zhang, T. (2018). Investigation of The Structure-Property Correlations of Pendent Functionalized Antimicrobial Polyurethanes [Master's thesis, University of Akron]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=akron1522936710295726

    APA Style (7th edition)

  • Zhang, Tian. Investigation of The Structure-Property Correlations of Pendent Functionalized Antimicrobial Polyurethanes . 2018. University of Akron, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=akron1522936710295726.

    MLA Style (8th edition)

  • Zhang, Tian. "Investigation of The Structure-Property Correlations of Pendent Functionalized Antimicrobial Polyurethanes ." Master's thesis, University of Akron, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=akron1522936710295726

    Chicago Manual of Style (17th edition)