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Magnet-assisted Layer-by-layer Assembly on Nanoparticles Based on 3D-printed Microfluidic Devices

Cheng, Kuan
http://rave.ohiolink.edu/etdc/view?acc_num=akron1554984796295339

Abstract Details

2019, Master of Science, University of Akron, Polymer Science.
The synthesis of core/shell structure nanoparticles based on the layer-by-layer assembly approach is potentially interesting for both biomedical and material engineering areas. Conventional methods face significant limitation in requiring tedious experiment time and unavoidable material impurity. This work describes a novel strategy to obtain encapsulated particles which improves the material purity and dramatically reduces the preparation time. An efficient, transparent, serpentine microfluidic mixer has been designed and fabricated through three-dimensional stereolithography technology. Chaotic mixing can be easily achieved by combining a series of “F” shape units in this device. Inherently negative charged iron oxide particles traveled in the fluidic channel by flow field and magnetic attraction, derived from a strong Niobium magnet. Additionally, a well-studied polyelectrolytes pair, poly(allylamine hydrochloride) (PAH)/poly(sodium 4-styrenesulfonate) (PSS), were injected from opposite inlets of the device in turn and mixed with particles vigorously in the stream. Our motivation is to simplify the conventional layer-by-layer assembly process in nanoscale. Results of zeta-potential data demonstrate the successive deposition of ten polymer layers on bare particles. Also, this method also gives a new perspective for the biomedical application like hyperthermia therapy.
Eric Amis (Advisor)
Matthew Becker (Committee Member)
61 p.
Polymers
Layer-by-layer; 3D-printing; Microfluidic

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Citations

  • Cheng, K. (2019). Magnet-assisted Layer-by-layer Assembly on Nanoparticles Based on 3D-printed Microfluidic Devices [Master's thesis, University of Akron]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=akron1554984796295339

    APA Style (7th edition)

  • Cheng, Kuan. Magnet-assisted Layer-by-layer Assembly on Nanoparticles Based on 3D-printed Microfluidic Devices . 2019. University of Akron, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=akron1554984796295339.

    MLA Style (8th edition)

  • Cheng, Kuan. "Magnet-assisted Layer-by-layer Assembly on Nanoparticles Based on 3D-printed Microfluidic Devices ." Master's thesis, University of Akron, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=akron1554984796295339

    Chicago Manual of Style (17th edition)

akron1554984796295339
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© 2019, all rights reserved.
This open access ETD is published by University of Akron and OhioLINK.