Skip to Main Content
Frequently Asked Questions
Submit an ETD
Global Search Box
Need Help?
Keyword Search
Participating Institutions
Advanced Search
School Logo
Files
File List
bgsu1300564452.pdf (2.06 MB)
ETD Abstract Container
Abstract Header
Molecular basis of group A colicin/TolA recognition in Enterobacter species
Author Info
Zook, Dana M.
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1300564452
Abstract Details
Year and Degree
2011, Master of Science (MS), Bowling Green State University, Biological Sciences.
Abstract
The Tol protein system is a set of proteins found between the cytoplasmic and outer membranes of Gram negative bacteria. The central component of this system is the protein TolA. The exact physiological function of both the protein system and TolA specifically remains to be determined; however data suggest a role in maintaining the integrity of the outer membrane. In addition to this hypothesized physiologic role, the Tol system has been shown to be parasitized by both filamentous bacteriophage and the toxic colicin proteins. The TolA protein is believed to facilitate the translocation of the phage and colicins across the periplasmic space. The present study characterizes phylogenetically conserved features of the TolA protein that contribute to sensitivity to group A colicins. This study provides insight into the molecular features of the protein-protein interactions involved in the translocation of group A colicins.
Committee
Ray Larsen, PhD (Advisor)
Scott Rogers, PhD (Committee Member)
Vipaporn Phuntumart, PhD (Committee Member)
Pages
65 p.
Subject Headings
Biology
;
Microbiology
;
Molecular Biology
Keywords
colicin
;
TolA
;
protein interactions
Recommended Citations
Refworks
EndNote
RIS
Mendeley
Citations
Zook, D. M. (2011).
Molecular basis of group A colicin/TolA recognition in Enterobacter species
[Master's thesis, Bowling Green State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1300564452
APA Style (7th edition)
Zook, Dana.
Molecular basis of group A colicin/TolA recognition in Enterobacter species.
2011. Bowling Green State University, Master's thesis.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1300564452.
MLA Style (8th edition)
Zook, Dana. "Molecular basis of group A colicin/TolA recognition in Enterobacter species." Master's thesis, Bowling Green State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1300564452
Chicago Manual of Style (17th edition)
Abstract Footer
Document number:
bgsu1300564452
Download Count:
1,047
Copyright Info
© 2011, all rights reserved.
This open access ETD is published by Bowling Green State University and OhioLINK.