Precision measurements of the A-dependence of the reaction p + A → μ+μ− + X at 800 GeV/c are reported in this thesis. Data were taken at Fermilab (E772) using a modified version of the large dimuon spectrometer in the Meson-East beamline. A total of 6 × 105 muon pairs were recorded for targets of D, C, Ca, Fe, and W. The kinematic region spanned by the data corresponds to a dimuon invariant mass of 3 ≤ Mμ+μ− ≤ 14 GeV, a Feynman-x of -0.1 ≤ xF ≤ 0.7, and a target parton momentum fraction of 0.03 ≤ x2 ≤ 0.30. Accurate relative target normalizations were achieved by careful monitoring of beam intensity and position, cyclic interchanges of targets, maintaining nearly 100% electronic livetime, and by use of precisely fabricated targets. The systematic errors in the relative yields are less than 2% for all targets.
Results are presented on the ratios of cross sections for nuclear targets relative to deuterium for the Drell-Yan process and for the production of the J/Ψ,Ψ′, and Υ quarkonia. These ratios are presented as functions of variables PT and xF, and versus x1 and x2 for the Drell-Yan process. Nuclear depletion at low-x2 is observed for the first time in the Drell-Ya n process. No nuclear enhancement of the antiquark distribution is observed in the region x2 ≥ 0.1. The data give tight constraints on models developed to explain nuclear medium effects in deep inelastic lepton scattering (EMC effect). Specifically, published models that have postulated a pion excess and 6-quark clusters are ruled out. The A-dependent behaviors on xF and PT for J/Ψ,Ψ′, and Υ production are also reported and compared with previous experiments. Substantial nuclear depletions are observed in both the xF and PT dependence. These depletions increase with increasing xF, and decrease with increasing PT.