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Hardware Implementation of a Stimulus Artifact Rejection Algorithm in Closed-loop Neuroprostheses

Soong, Chia-Wei

Abstract Details

2008, Master of Sciences (Engineering), Case Western Reserve University, Electrical Engineering and Computer Science - Electrical Engineering.
Due to their large amplitudes, stimulus artifacts can easily saturate neural recording amplifiers and hamper neural signal analysis during recording. In this work, we present a prototype stimulus artifact rejection (SAR) system, which is based on the template subtraction technique. A reference template signal of the stimulus artifact is generated by a pseudo-higher sampling rate averaging method, which is then subtracted from the original contaminated signal to reveal the desired neural activity. Measurement results from a proof-of-concept discrete implementation of the SAR system indicate that it is highly effective in reducing the amplitude of the stimulus artifacts. The system exhibits a stimulus artifact rejection of ~10-15 dB at the rising and falling edges of the artifact (where it is changing rapidly with time) and successfully recovers microvolt-range neural action potentials from the slowly decaying tail of the artifact. Compared to the existing subtraction-based SAR algorithms, additional stimulus artifact suppression of ~5.5 dB is achieved in this work.
Pedram Mohseni (Committee Chair)
Frank Merat (Other)
Marc Buchner (Other)

Recommended Citations

Citations

  • Soong, C.-W. (2008). Hardware Implementation of a Stimulus Artifact Rejection Algorithm in Closed-loop Neuroprostheses [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1216397239

    APA Style (7th edition)

  • Soong, Chia-Wei. Hardware Implementation of a Stimulus Artifact Rejection Algorithm in Closed-loop Neuroprostheses. 2008. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1216397239.

    MLA Style (8th edition)

  • Soong, Chia-Wei. "Hardware Implementation of a Stimulus Artifact Rejection Algorithm in Closed-loop Neuroprostheses." Master's thesis, Case Western Reserve University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=case1216397239

    Chicago Manual of Style (17th edition)