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Prevalence and correlates of alpha-delta sleep in major depressive disorders

Budur, Kumaraswamy
http://rave.ohiolink.edu/etdc/view?acc_num=case1274987413

Abstract Details

2010, Master of Sciences, Case Western Reserve University, Clinical Research.
OBJECTIVE Major depressive disorder (MDD) is associated with sleep disturbances. An electroencephalographic (EEG) pattern of alpha wave intrusion in delta wave sleep (alpha-delta sleep) is observed in some subjects with MDD. The treatment-resistant symptoms in MDD, non-restorative sleep and fatigue, are associated with alpha-delta sleep. The objective of this study is to identify the prevalence and clinical correlates of alpha-delta sleep in MDD. METHODS Retrospective study of 150 polysomnograms of subjects greater than 18 years (75 each with and with no MDD). The percent of delta waves with alpha intrusion was collected and analyzed. RESULTS MDD patients had significanly higher alpha-delta sleep. MDD patients with high alpha-delta sleep were at 3.15 greater odds to have excessive daytime sleepiness. CONCLUSIONS Patients with MDD have a higher prevalence of alpha-delta sleep. Alpha-Delta sleep is associated with daytime sleepiness in MDD-patients.
Robert Fox, MD (Committee Chair)
Douglas Einstadster, MD (Committee Member)
Kingman Strohl, MD (Committee Member)
64 p.
Health Care; Mental Health
Major depressive disorder; alpha-delta sleep; excessive daytime sleepiness; insomnia; fatigue; non-restorative sleep

Recommended Citations

Citations

  • Budur, K. (2010). Prevalence and correlates of alpha-delta sleep in major depressive disorders [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1274987413

    APA Style (7th edition)

  • Budur, Kumaraswamy. Prevalence and correlates of alpha-delta sleep in major depressive disorders. 2010. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1274987413.

    MLA Style (8th edition)

  • Budur, Kumaraswamy. "Prevalence and correlates of alpha-delta sleep in major depressive disorders." Master's thesis, Case Western Reserve University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1274987413

    Chicago Manual of Style (17th edition)

case1274987413
1,749
© 2010, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.