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THE STATE AND FUTURE OF CLOSED LOOP INSULIN PUMPS / ARTIFICIAL PANCREAS

Umapathy, Chandravadhana

Abstract Details

2011, Master of Sciences, Case Western Reserve University, Biology.
With the advent of continuous glucose monitoring therapy and support from the Juvenile Diabetes Research Foundation (JDRF) the Artificial Pancreas Project has been developed to understand the clinical and economic benefits of closed loop systems and continuous glucose monitors. These complex systems are intended to completely take over the insulin dosing and keep the blood sugar under target range. The critical factor in the entire artificial pancreas equation is the insulin. The fast acting analogs have been altered to improve their pharmacokinetic profiles and decrease the time they take to enter the bloodstream. Next generation insulin analogues offer faster kinetics, efficient blood glucose control and better automation for the closed loop systems. This thesis deals with the challenges and the various solutions offered to counter the colossal task of "closed loop" solutions.
Christopher Cullis, PHD (Committee Member)
Richard Berenson (Advisor)
Jolly Emmitt, PHD (Committee Member)
Robin Snyder, PHD (Committee Chair)
89 p.

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Citations

  • Umapathy, C. (2011). THE STATE AND FUTURE OF CLOSED LOOP INSULIN PUMPS / ARTIFICIAL PANCREAS [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1301604304

    APA Style (7th edition)

  • Umapathy, Chandravadhana. THE STATE AND FUTURE OF CLOSED LOOP INSULIN PUMPS / ARTIFICIAL PANCREAS. 2011. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1301604304.

    MLA Style (8th edition)

  • Umapathy, Chandravadhana. "THE STATE AND FUTURE OF CLOSED LOOP INSULIN PUMPS / ARTIFICIAL PANCREAS." Master's thesis, Case Western Reserve University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1301604304

    Chicago Manual of Style (17th edition)