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Neurodevelopmental Outcomes of Extremely Low Gestational Age Neonates With Low Grade Intraventricular-Periventricular Hemorrhage

Payne, Allison H.
http://rave.ohiolink.edu/etdc/view?acc_num=case1323204387

Abstract Details

2011, Master of Sciences, Case Western Reserve University, Clinical Research.
Low grade intraventricular-periventricular hemorrhage (IV-PVH) is a common neurologic morbidity among extremely low gestational age (ELGA, < 27 weeks gestation) neonates yet the outcomes associated with this morbidity are poorly understood. We sought to determine the effect of low grade IV-PVH on neurodevelopmental outcomes at 18-22 months corrected age using a three year cohort of a large multicenter database. Mixed effects regression modeling was utilized to account for potential confounders including gestational age, gender, race/ethnicity, chorioamnionitis, antenatal and/or postnatal steroids, high frequency ventilation, sepsis, and patent ductus arteriosus, as well as center differences. There were no significant differences in unadjusted or adjusted motor, cognitive, language, or composite mild or moderate-severe neurodevelopmental impairment outcomes when comparing ELGA infants with low grade IV-PVH to ELGA infants without evidence of IV-PVH on cranial ultrasound.
Deanne Wilson-Costello, MD (Advisor)
Douglas Einstadter, MD, MS (Committee Member)
Michele Walsh, MD, MS (Committee Member)
Anna Maria Hibbs, MD, MS (Committee Member)
40 p.
Epidemiology; Medicine
neurodevelopmental outcomes; prematurity; intraventricular hemorrhage; intraventricular-periventricular hemorrhage; ELGA

Recommended Citations

Citations

  • Payne, A. H. (2011). Neurodevelopmental Outcomes of Extremely Low Gestational Age Neonates With Low Grade Intraventricular-Periventricular Hemorrhage [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1323204387

    APA Style (7th edition)

  • Payne, Allison. Neurodevelopmental Outcomes of Extremely Low Gestational Age Neonates With Low Grade Intraventricular-Periventricular Hemorrhage. 2011. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1323204387.

    MLA Style (8th edition)

  • Payne, Allison. "Neurodevelopmental Outcomes of Extremely Low Gestational Age Neonates With Low Grade Intraventricular-Periventricular Hemorrhage." Master's thesis, Case Western Reserve University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1323204387

    Chicago Manual of Style (17th edition)

case1323204387
977
© 2011, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.