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UTILIZATION OF FLUORESCENCE MOLECULAR IMAGING TO OPTIMIZE RADIONUCLIDE IMAGING

Somoza, Eduardo A., Jr

Abstract Details

2012, Master of Sciences (Engineering), Case Western Reserve University, Biomedical Engineering.
Fluorescence imaging has been used by the radiopharmaceutical industry since inception because of its comparable sensitivity to PET/SPECT modalities and ability to study biological processes without using non-ionizing radiation. Radiolabeling schemes are developed for fluorescent molecular probes showing potential for clinical PET or SPECT applications. The purpose of this thesis is to use fluorescent molecular imaging to determine the potential of a compound for the early detection of demyelination in the central nervous system (CNS) and develop a delivery system for a molecular inhibitor of the BER pathway that could potentially be used in radionuclide imaging.
Wang Yanming, PhD (Committee Chair)
David Wilson, PhD (Committee Member)
Xin Yu, PhD (Committee Member)
46 p.

Recommended Citations

Citations

  • Somoza, Jr, E. A. (2012). UTILIZATION OF FLUORESCENCE MOLECULAR IMAGING TO OPTIMIZE RADIONUCLIDE IMAGING [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1338904705

    APA Style (7th edition)

  • Somoza, Jr, Eduardo. UTILIZATION OF FLUORESCENCE MOLECULAR IMAGING TO OPTIMIZE RADIONUCLIDE IMAGING. 2012. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1338904705.

    MLA Style (8th edition)

  • Somoza, Jr, Eduardo. "UTILIZATION OF FLUORESCENCE MOLECULAR IMAGING TO OPTIMIZE RADIONUCLIDE IMAGING." Master's thesis, Case Western Reserve University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=case1338904705

    Chicago Manual of Style (17th edition)