Skip to Main Content
 

Global Search Box

 
 
 
 

Files

File List


case1339099818.pdf (2.91 MB)

ETD Abstract Container

Abstract Header

PEDIGREE QUERY, VISUALIZATION, AND GENETIC CALCULATIONS TOOL

Kurtcephe, Murat
http://rave.ohiolink.edu/etdc/view?acc_num=case1339099818

Abstract Details

2012, Master of Sciences, Case Western Reserve University, EECS - Computer and Information Sciences.
Family trees, a.k.a. pedigrees, are becoming increasingly important in human genetics, as pedigrees can be utilized to trace a genetic disorder or trait and to calculate disease risks. In this study, we present a new system for pedigree query, visualization, and genetic calculations. A novel query interface is proposed where users can form complicated queries via an easy-to-use graphical user interface with no need for any knowledge of high level query language such as SQL or XPath. A graph encoding method called NodeCodes enables our system to efficiently evaluate relationship-based queries without traversing the graph or using recursive query calls. The visualization of the pedigree data as a dynamic drawing enables the analysis of query results in a more understandable form. The system also provides genetic calculations including inbreeding, kinship, and identity coefficients. Proposed system performs these calculations by using path-based formulas coupling with NodeCodes to achieve efficiency and scalability.
Zehra M. Ozsoyo¿¿¿¿lu, PhD (Committee Chair)
Jing Li, PhD (Committee Member)
Mehmet Koyut¿¿¿¿rk, PhD (Committee Member)
100 p.
Computer Science
pedigree; pedigree query; graphical query interface; graph query

Recommended Citations

Citations

  • Kurtcephe, M. (2012). PEDIGREE QUERY, VISUALIZATION, AND GENETIC CALCULATIONS TOOL [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1339099818

    APA Style (7th edition)

  • Kurtcephe, Murat. PEDIGREE QUERY, VISUALIZATION, AND GENETIC CALCULATIONS TOOL. 2012. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1339099818.

    MLA Style (8th edition)

  • Kurtcephe, Murat. "PEDIGREE QUERY, VISUALIZATION, AND GENETIC CALCULATIONS TOOL." Master's thesis, Case Western Reserve University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=case1339099818

    Chicago Manual of Style (17th edition)

case1339099818
2,823
© 2012, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.