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Thesis Robin Davis .pdf (5.22 MB)

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Characterization of Two Hair Cell Proteins in the Zebrafish Lateral Line

Woods, Robin Davis
http://rave.ohiolink.edu/etdc/view?acc_num=case1465471067

Abstract Details

2016, Master of Sciences, Case Western Reserve University, Biology.
Mechanotransduction is an important mechanism found in several sensory systems. It is the act of transforming a mechanical stimulus into an electrical response, the language of the nervous system. In the auditory, vestibular, and lateral line system, the sensory receptor of mechanosensation is the hair cell, a cell so named because of the bundle of stereocilia on its apical surface. When the stereocilia are deflected as a result of the movement of the fluid surrounding them, ion channels located at their tips open and cations enter, creating an electrical current. This thesis examines the function of two proteins found in hair cells, using gene-specific knockout zebrafish lines. The experiments performed help to elucidate the complex diversity of proteins involved in the hair cell.
Brian McDermott, Jr (Advisor)
Hillel Chiel (Committee Member)
Ruben Stepanyan (Committee Member)
Ryan Martin (Committee Chair)
Biology; Neurobiology

Recommended Citations

Citations

  • Woods, R. D. (2016). Characterization of Two Hair Cell Proteins in the Zebrafish Lateral Line [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1465471067

    APA Style (7th edition)

  • Woods, Robin. Characterization of Two Hair Cell Proteins in the Zebrafish Lateral Line. 2016. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1465471067.

    MLA Style (8th edition)

  • Woods, Robin. "Characterization of Two Hair Cell Proteins in the Zebrafish Lateral Line." Master's thesis, Case Western Reserve University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1465471067

    Chicago Manual of Style (17th edition)

case1465471067
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This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.