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DETECTION AND QUANTIFICATION OF CORONARY CALCIUM FROM DUAL ENERGY CHEST X-RAYS: PHANTOM FEASIBILITY STUDY

Zhou, Bo
http://rave.ohiolink.edu/etdc/view?acc_num=case1481216785398625

Abstract Details

2016, Master of Sciences, Case Western Reserve University, Biomedical Engineering.
We have demonstrated the ability to identify coronary calcium using non-gated, 2-shot, dual energy (DE) chest x-ray imaging. Here we used digital simulations to characterize DE calcium signals and the role of potential confounds such as beam hardening, scatter estimation, cardiac motion, and pulmonary artery pulsation. For the DE calcium signal, we will consider quantification, as compared to CT calcium score. We created digital 3D phantoms including heart, lung, coronary calcium, spine, ribs, pulmonary artery, and adipose. We simulated x-ray acquisitions with x-ray spectra, energy dependent attenuation, scatter, ideal detector, and automatic exposure control (AEC). Phantoms allowed us to independently vary adipose thickness, cardiac motion, etc. to study the potential confounds. We used specialized dual energy coronary calcium (DECC) processing that includes corrections for scatter and beam hardening. Simulations indicate that proper DECC processing can faithfully recover coronary calcium signals. Potential confounds above are all manageable. Simulations are valuable as we continue to optimize DE coronary calcium image processing and quantitative analysis.
David Wilson (Committee Chair)
Anant Madabushi (Committee Member)
Robert Gilkeson (Committee Member)
81 p.
Biomedical Engineering
Medical imaging, Dual energy x-ray imaging, Coronary artery calcification, Chest radiography

Recommended Citations

Citations

  • Zhou, B. (2016). DETECTION AND QUANTIFICATION OF CORONARY CALCIUM FROM DUAL ENERGY CHEST X-RAYS: PHANTOM FEASIBILITY STUDY [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1481216785398625

    APA Style (7th edition)

  • Zhou, Bo. DETECTION AND QUANTIFICATION OF CORONARY CALCIUM FROM DUAL ENERGY CHEST X-RAYS: PHANTOM FEASIBILITY STUDY. 2016. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1481216785398625.

    MLA Style (8th edition)

  • Zhou, Bo. "DETECTION AND QUANTIFICATION OF CORONARY CALCIUM FROM DUAL ENERGY CHEST X-RAYS: PHANTOM FEASIBILITY STUDY." Master's thesis, Case Western Reserve University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1481216785398625

    Chicago Manual of Style (17th edition)

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© 2016, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.