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MSc Thesis. Valentine Siba_CWRU2017.pdf (2.95 MB)

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EFFECT OF BED NETS ON ACQUIRED HUMORAL IMMUNITY TO PLASMODIUM FALCIPARUM ANTIGENS IN CHILDREN FROM MUGIL, MADANG PROVINCE, PAPUA NEW GUINEA.

Siba, Valentine
http://rave.ohiolink.edu/etdc/view?acc_num=case1485675594752553

Abstract Details

2017, Master of Sciences, Case Western Reserve University, Biology.
Papua New Guinea (PNG) is endemic to P. falciparum and has the highest burden of malaria outside of Africa with an estimated 1.36 million cases each year. Malaria control and elimination efforts have proven to reduce the burden of the disease in PNG through the distribution and use of insecticide treated nets (INTs) especially in highly endemic areas. Evidence suggests that antibodies mediate protection against infection, and immunity against malaria is associated with repeated exposure to the disease. This study is focused on comparing antibody levels between children who did not use ITNs and children who used ITNs in a malaria endemic region of PNG. The overall results showed higher levels of antibody responses to P. falciparum in the group of children who did not use ITNs and low antibody responses to P. falciparum in the group of children who used ITNs. This suggests that the use of ITNs may have an effect on immunity to malaria in children.
Michael Benard, PhD (Committee Chair)
James Kazura, MD (Advisor)
Emmitt Jolly, PhD (Committee Member)
Ryan Martin, PhD (Committee Member)
63 p.
Biology; Immunology

Recommended Citations

Citations

  • Siba, V. (2017). EFFECT OF BED NETS ON ACQUIRED HUMORAL IMMUNITY TO PLASMODIUM FALCIPARUM ANTIGENS IN CHILDREN FROM MUGIL, MADANG PROVINCE, PAPUA NEW GUINEA. [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1485675594752553

    APA Style (7th edition)

  • Siba, Valentine. EFFECT OF BED NETS ON ACQUIRED HUMORAL IMMUNITY TO PLASMODIUM FALCIPARUM ANTIGENS IN CHILDREN FROM MUGIL, MADANG PROVINCE, PAPUA NEW GUINEA. 2017. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1485675594752553.

    MLA Style (8th edition)

  • Siba, Valentine. "EFFECT OF BED NETS ON ACQUIRED HUMORAL IMMUNITY TO PLASMODIUM FALCIPARUM ANTIGENS IN CHILDREN FROM MUGIL, MADANG PROVINCE, PAPUA NEW GUINEA." Master's thesis, Case Western Reserve University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=case1485675594752553

    Chicago Manual of Style (17th edition)

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© 2017, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.