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Ontology-driven Web-based Medical Image Sharing Interface for Epilepsy Research

Wu, Xi
http://rave.ohiolink.edu/etdc/view?acc_num=case1496660866436638

Abstract Details

2017, Master of Sciences, Case Western Reserve University, EECS - Computer Engineering.
Epilepsy is a disorder of the brain that causes recurrent seizures. In all the epilepsy-related deaths, 7.5 to 17 percent are from Sudden Unexpected Death in Epilepsy (SUDEP) which has an incidence rate of up to 9 per 1000 patient-years in epilepsy surgery candidates. Possible factors of SUDEP have been explored but the precise mechanism remains mysterious. [1] Neuroimaging techniques such as MRI provides a critical data source for investigators to research and share a larger cohort of potential SUDEP patients. Sharing neuroimaging data to engage more researchers is critical since the image data we collected on an SUDEP patient is still limited and not able to grow. To address the unique challenges of sharing neuroimaging data across institutions with good semantic precision, ImageSFERE - a web-based platform for Image Sharing for Epilepsy Research is developed. ImageSFERE features a dedicated questionnaire and standardized epilepsy neuroimaging common data elements to capture patient-related image metadata, enhance the system efficiency, and enable precise and federated queries. The multi-section questionnaire consists of 244 questions were well-designed to record different aspects of patient information. ImageSFERE also enables slice-level and repository-level image annotations which improve the relevance of images and annotations. We have successfully processed 8 separated repositories (over 23GB of data) of DICOM patient de-identified images from different institutions using ImageSFERE uploading interface and made available for query.
Pan Li (Committee Chair)
GQ Zhang (Advisor)
Rong Xu (Committee Member)
60 p.
Bioinformatics; Systems Design

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Citations

  • Wu, X. (2017). Ontology-driven Web-based Medical Image Sharing Interface for Epilepsy Research [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1496660866436638

    APA Style (7th edition)

  • Wu, Xi. Ontology-driven Web-based Medical Image Sharing Interface for Epilepsy Research. 2017. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1496660866436638.

    MLA Style (8th edition)

  • Wu, Xi. "Ontology-driven Web-based Medical Image Sharing Interface for Epilepsy Research." Master's thesis, Case Western Reserve University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=case1496660866436638

    Chicago Manual of Style (17th edition)

case1496660866436638
312
© 2017, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.