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Phillippi.Kathryn Master's thesis.pdf (6.23 MB)

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Arthritis as First Presenting Symptom of Inflammatory Bowel Disease: A Case Control Study

Phillippi, Kathryn
http://orcid.org/0000-0002-3144-6721
http://rave.ohiolink.edu/etdc/view?acc_num=case1496789004675552

Abstract Details

2017, Master of Sciences, Case Western Reserve University, Clinical Research.
Background: Inflammatory bowel disease (lBD) is frequently associated with arthralgia and arthritis. We hypothesized that differences exist in initial laboratory values and body measurements that can distinguish !BD associated arthritis from other forms of juvenile idiopathic arthritis (JlA) prior to the diagnoses of lBD. Methods: A retrospective case control study of children who presented with joint pain without overt gastrointestinal symptoms and who were subsequently diagnosed with IBD was performed. Age and gender matched controls were identified from children with JlA. Body morphometrics and laboratory findings were extracted by chart review. Results: 12 subjects and 24 controls were identified. Univariate analysis demonstrated that subjects with IBD associated arthritis had significantly lower weight, hemoglobin, albumin levels and higher CRP and ESR values. Multivariate analysis showed subjects with |BD-associated arthritis had elevated CRP and lower weight. Conclusion: These data suggest that in subjects presenting with arthritis, elevated CRP and lower weight percentile, IBD should be excluded causative.
Elizabeth Brooks, MD, PhD (Committee Chair)
15 p.
Medicine
Inflammatory bowel disease; IBD; Pediatrics; Juvenile Idiopathic Arthritis; JIA; arthritis

Recommended Citations

Citations

  • Phillippi, K. (2017). Arthritis as First Presenting Symptom of Inflammatory Bowel Disease: A Case Control Study [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1496789004675552

    APA Style (7th edition)

  • Phillippi, Kathryn. Arthritis as First Presenting Symptom of Inflammatory Bowel Disease: A Case Control Study. 2017. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1496789004675552.

    MLA Style (8th edition)

  • Phillippi, Kathryn. "Arthritis as First Presenting Symptom of Inflammatory Bowel Disease: A Case Control Study." Master's thesis, Case Western Reserve University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=case1496789004675552

    Chicago Manual of Style (17th edition)

case1496789004675552
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© 2017, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.