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3D Microarray: How 3D Bioprinting can Reduce the Growing Cost of Pharmaceutical Drug Development

Yen, Terence, Yen
http://orcid.org/0000-0001-7465-4873
http://rave.ohiolink.edu/etdc/view?acc_num=case1498946531798367

Abstract Details

2017, Master of Sciences, Case Western Reserve University, Biology.
The process of drug development continues to grow longer and more expensive every year. This is due in large part to the growing rate of drug candidate failure in both the preclinical discovery phase and the clinical trial phase. Through literary analysis, we will review both the process of developing a new drug, and the real capitalized cost of drug development. 3D bioprinting, and more specifically, the high throughput screening technology presented by 3D Microarray Inc. offers a potential solution to this problem. Miniaturized human tissue constructs created through microarray bioprinting could drastically reduce the cost of drug development by shortening the time involved in drug discovery, as well as aiding in the disqualification of inappropriate candidates at a much earlier stage. 3D Microarray’s bioprinting technology should be explored further, and the company has several business model options to consider as they move forward.
Christopher Cullis (Advisor)
Moo-Yeal Lee (Committee Member)
Jean Welter (Committee Member)
Mike Benard (Committee Chair)
56 p.
Biology; Chemical Engineering
3D bioprinting; bioprinting; in vitro toxicology; drug development

Recommended Citations

Citations

  • Yen, Yen, T. (2017). 3D Microarray: How 3D Bioprinting can Reduce the Growing Cost of Pharmaceutical Drug Development [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1498946531798367

    APA Style (7th edition)

  • Yen, Yen, Terence. 3D Microarray: How 3D Bioprinting can Reduce the Growing Cost of Pharmaceutical Drug Development. 2017. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1498946531798367.

    MLA Style (8th edition)

  • Yen, Yen, Terence. "3D Microarray: How 3D Bioprinting can Reduce the Growing Cost of Pharmaceutical Drug Development." Master's thesis, Case Western Reserve University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=case1498946531798367

    Chicago Manual of Style (17th edition)

case1498946531798367
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© 2017, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.