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Information theoretic analysis of a biological signal transduction system_Shu Wang.pdf (9.08 MB)
ETD Abstract Container
Abstract Header
Information Theoretic Analysis of A Biological Signal Transduction System
Author Info
Wang, Shu
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=case1526393370364409
Abstract Details
Year and Degree
2018, Master of Sciences, Case Western Reserve University, Biology.
Abstract
Signal transduction is a process by which living cells detect and respond to changes in their environment, including signaling, reception, transduction, and response reactions. Information theory as introduced by Shannon uses mutual information, the difference between entropy of output and entropy of output given input, to estimate uncertainty in message transmission processes. Neurotransmission is a typical signal transduction process in which the neurotransmitter works as a signaling molecule, carrying information from the source to an associated receptor. Viewing the input and output signals as point processes, we apply information theory to analyze its communication capabilities. This thesis provides a detailed glutamate simulation procedure and its mutual information analysis in MATLAB, and describes how information theory applies to a neurotransmission simulation.
Committee
Peter Thomas (Advisor)
Pages
50 p.
Subject Headings
Biology
;
Information Systems
;
Mathematics
Keywords
Neurotransmission, Information Theory, Mutual Information
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Citations
Wang, S. (2018).
Information Theoretic Analysis of A Biological Signal Transduction System
[Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1526393370364409
APA Style (7th edition)
Wang, Shu.
Information Theoretic Analysis of A Biological Signal Transduction System.
2018. Case Western Reserve University, Master's thesis.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=case1526393370364409.
MLA Style (8th edition)
Wang, Shu. "Information Theoretic Analysis of A Biological Signal Transduction System." Master's thesis, Case Western Reserve University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1526393370364409
Chicago Manual of Style (17th edition)
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Document number:
case1526393370364409
Download Count:
191
Copyright Info
© 2018, some rights reserved.
Information Theoretic Analysis of A Biological Signal Transduction System by Shu Wang is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. Based on a work at etd.ohiolink.edu.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.