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Thesis_Lehr.pdf (1.78 MB)
ETD Abstract Container
Abstract Header
Extremes of Age Decrease Survival After Lung Transplant
Author Info
Lehr, Carli J
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=case152909506004063
Abstract Details
Year and Degree
2018, Master of Sciences, Case Western Reserve University, Clinical Research.
Abstract
The aim of this study was to determine impact of the age of lung transplant recipients on survival after lung transplant. We used data from the Scientific Registry of Transplant Recipients and studied 14,253 adult lung transplant recipients between January 1, 2006 and February 19, 2015. Survival was estimated using a non-proportional hazard model and random-survival forest methodology to examine risk-factors for death. Risk factors were obtained for the entire population and additional age-specific risk factors were identified for each age category. There were 1,098 (7.7%) recipients < 30 years, 4,201 (29.5%) 30-55 years, and 8,954 (62.8%) > 55 years of age. The youngest and oldest recipients experienced the lowest post-transplant survival. Risk factors for death for the entire population included extremes of age, higher creatinine, single lung transplant, hospitalization prior to transplant, and increased bilirubin. Age was the most significant risk factor for death at all time-points following transplant.
Committee
Maryam Valapour , MD, MPP (Committee Chair)
Reena Mehra, MD, MS (Advisor)
Elliott Dasenbrook, MD, MS (Committee Member)
Pages
49 p.
Subject Headings
Medicine
Keywords
lung transplant
;
age
;
outcomes
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Citations
Lehr, C. J. (2018).
Extremes of Age Decrease Survival After Lung Transplant
[Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case152909506004063
APA Style (7th edition)
Lehr, Carli.
Extremes of Age Decrease Survival After Lung Transplant.
2018. Case Western Reserve University, Master's thesis.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=case152909506004063.
MLA Style (8th edition)
Lehr, Carli. "Extremes of Age Decrease Survival After Lung Transplant." Master's thesis, Case Western Reserve University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case152909506004063
Chicago Manual of Style (17th edition)
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Document number:
case152909506004063
Download Count:
234
Copyright Info
© 2018, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.