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WEIGHT LOSS MEDICATION: A PRELIMINARY STUDY TO ASSESS IF IT WORKS

Mohamed Hag, Amani MI

Abstract Details

2019, Master of Sciences, Case Western Reserve University, Clinical Research.
Background: Obesity is a rising global health problem (1,2). It is associated with increased incidence of chronic diseases such as Type 2 diabetes, heart disease, hypertension, cancer and mortality (3-6). Life style intervention including dietary modification and exercise are suggested as the first step to treat obesity (7). However, successful weight loss and maintenance of the results maybe hard to achieve. In these circumstances, pharmacotherapy is indicated (8). Objective: This study represents an initial step in assessing comparative efficacy of weight loss medications. We hypothesized that weight loss medications would be differentially associated with observed weight loss over time in our study sample. Methods: A retrospective study of 543 patients with obesity recruited from the Cleveland Clinic Bariatric and Metabolic Institute between January 2000 and December 2013 who received weight loss medications, which included five FDA approved medications. Results: Of the 543 patients receiving weight loss medication, 67% of the study cohort showed weight loss of 2.5% at six months, and 62% showed weight loss of 2.6% at 12 months. Conclusion: The study provided preliminary evidence that weight loss medications can be useful in patients who have not achieved weight loss with life style modifications alone.
James Spilsbury, PhD/MPH (Committee Chair)
Bartolome Burguera, MD/PhD (Committee Member)
Douglas Einstadter, MD (Committee Member)
35 p.

Recommended Citations

Citations

  • Mohamed Hag, A. M. (2019). WEIGHT LOSS MEDICATION: A PRELIMINARY STUDY TO ASSESS IF IT WORKS [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1554472321010433

    APA Style (7th edition)

  • Mohamed Hag, Amani. WEIGHT LOSS MEDICATION: A PRELIMINARY STUDY TO ASSESS IF IT WORKS. 2019. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1554472321010433.

    MLA Style (8th edition)

  • Mohamed Hag, Amani. "WEIGHT LOSS MEDICATION: A PRELIMINARY STUDY TO ASSESS IF IT WORKS." Master's thesis, Case Western Reserve University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1554472321010433

    Chicago Manual of Style (17th edition)