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THE INFLUENCE OF EXECUTIVE FUNCTION, ADAPTIVE FUNCTION, ACADEMIC ACHIEVEMENT ON HEALTH RELATED QUALITY OF LIFE IN CHILDREN WITH CHRONIC KIDNEY DISEASE

AL-Hamed, Arwa Abdulaziz
http://orcid.org/0000-0002-8008-8705
http://rave.ohiolink.edu/etdc/view?acc_num=case1555099896433292

Abstract Details

2019, Doctor of Philosophy, Case Western Reserve University, Nursing.
The aim of this study was to examine the relationship between executive function (EF), adaptive function (AF), academic achievement (AA), and to identify their relationship with health related quality of life (HRQOL) in children with chronic kidney disease (CKD). A cross-sectional design was used for this secondary data analysis of children from across the United States and Canada with mild to moderate CKD who receive care at hospitals associated with the Chronic Kidney Disease in Children study (CKiD). Data were collected using the Conner’s Continuous Performance Testing-II, Behavior Rating Inventory of Executive Functioning (BRIEF), Behavior Assessment System for Children-2, Wechsler Individual Achievement Test-II-Abbreviated and Pediatric Quality of Life Inventory. The children (N= 243) were mostly between 13 to 17 years of age (45%), 75 %, were Caucasian and 59% were male. A majority of the mothers (55%) had some college or baccalaureate degree and a household income above 31,000% annually (74%). The majority of children (76%) had a type of non-glomerular CKD; 50 % had CKD Stage 2 & 3. Children with CKD had lower HRQOL compared to their healthy peers with school functioning being the most affected area. Most scores for the EF, AF, and AA placed children with CKD within an age-appropriate range. However, there was a high percentage of children (23%- 43%) scoring more than 1 SD below the mean for EF, AF, and AA, indicating an increased risk for neurocognitive impairments. The hierarchical multiple regression analysis indicated that EF, AF, and AA accounted for 36 % of the variance in HRQOL but increased to 40% of the variance with the addition of covariates. Poor EF (Global Executive Composite), AF (Internalizing Problems [e.g. depressive symptoms, and anxiety]), and AA significantly predicted lower HRQOL. With the addition of covariates, only EF and AF remained significant, while high maternal education significantly predicted higher HRQOL, and anemia significantly predicted lower HRQOL. While the mediation effect of AA on the relationship between EF and HRQOL was not supported in this study, the results suggest that AF (Internalizing Problems) partially mediated the relationship between EF and HRQOL. This study underscores the need for an interdisciplinary approach (school nurses, teachers, psychologists, pediatric nephrologist) to tailor interventions that optimize EF, AF, and AA, and enhance HRQOL in children with mild to moderate CKD.
Valerie Toly (Committee Chair)
256 p.
Health Care; Nursing

Recommended Citations

Citations

  • AL-Hamed, A. A. (2019). THE INFLUENCE OF EXECUTIVE FUNCTION, ADAPTIVE FUNCTION, ACADEMIC ACHIEVEMENT ON HEALTH RELATED QUALITY OF LIFE IN CHILDREN WITH CHRONIC KIDNEY DISEASE [Doctoral dissertation, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1555099896433292

    APA Style (7th edition)

  • AL-Hamed, Arwa. THE INFLUENCE OF EXECUTIVE FUNCTION, ADAPTIVE FUNCTION, ACADEMIC ACHIEVEMENT ON HEALTH RELATED QUALITY OF LIFE IN CHILDREN WITH CHRONIC KIDNEY DISEASE. 2019. Case Western Reserve University, Doctoral dissertation. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1555099896433292.

    MLA Style (8th edition)

  • AL-Hamed, Arwa. "THE INFLUENCE OF EXECUTIVE FUNCTION, ADAPTIVE FUNCTION, ACADEMIC ACHIEVEMENT ON HEALTH RELATED QUALITY OF LIFE IN CHILDREN WITH CHRONIC KIDNEY DISEASE." Doctoral dissertation, Case Western Reserve University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1555099896433292

    Chicago Manual of Style (17th edition)

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© 2019, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.