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DEVELOPMENT OF A DISCRETE COMPONENT PLATFORM TOWARDS LOW-POWER, WIRELESS, CONDUCTIVITY-CORRECTED, CONDUCTANCE-BASED BLADDER VOLUME ESTIMATION IN FELINES

Abstract Details

2019, Master of Sciences, Case Western Reserve University, EECS - Electrical Engineering.
New research tools are essential to understanding neural control of the lower urinary tract (LUT) and could enable new treatments or neuroprosthesis to eliminate incontinence. Modern technologies enable real-time, catheter-free monitoring of bladder pressure, however variations in physiology among animals and people complicate interpretation of pressure data without bladder volume information. To date, no available technology achieves catheter-free, chronic monitoring of bladder volume. This thesis describes the design of a fully-wireless device for conductivity-corrected conductance measurements of fluid volume in a catheter-free system. The device consists of two electrodes, one sensing anode, and a microcontroller, and is small enough for surgical implantation within the bladder lumen. In-vitro benchtop testing demonstrated fluid volume prediction with <5mL mean error below 40mL and a worst-case mean error of 13mL near full-scale volume. These results indicate that conductance-based volume sensing of the urinary bladder is a feasible method for real-time catheter-free urine volume measurement.
Christian Zorman, Dr. (Committee Chair)
Margot Damaser, Dr. (Committee Member)
Soumyajit Mandal, Dr. (Committee Member)
Steve Majerus, Dr. (Committee Member)
113 p.

Recommended Citations

Citations

  • McAdams, I. (2019). DEVELOPMENT OF A DISCRETE COMPONENT PLATFORM TOWARDS LOW-POWER, WIRELESS, CONDUCTIVITY-CORRECTED, CONDUCTANCE-BASED BLADDER VOLUME ESTIMATION IN FELINES [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1560442028426129

    APA Style (7th edition)

  • McAdams, Ian. DEVELOPMENT OF A DISCRETE COMPONENT PLATFORM TOWARDS LOW-POWER, WIRELESS, CONDUCTIVITY-CORRECTED, CONDUCTANCE-BASED BLADDER VOLUME ESTIMATION IN FELINES. 2019. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1560442028426129.

    MLA Style (8th edition)

  • McAdams, Ian. "DEVELOPMENT OF A DISCRETE COMPONENT PLATFORM TOWARDS LOW-POWER, WIRELESS, CONDUCTIVITY-CORRECTED, CONDUCTANCE-BASED BLADDER VOLUME ESTIMATION IN FELINES." Master's thesis, Case Western Reserve University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1560442028426129

    Chicago Manual of Style (17th edition)