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Nick_Vitale_Thesis_FINAL (1).pdf (5.81 MB)

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A Bluetooth Low Energy-Enabled Neural Microsystem for Activity-Dependent Intracortical Microstimulation in Non-Human Primates

Vitale, Nicholas Heywood
http://rave.ohiolink.edu/etdc/view?acc_num=case156534949054962

Abstract Details

2020, Master of Sciences, Case Western Reserve University, EECS - Electrical Engineering.
This thesis reports on the design and development of a Bluetooth Low Energy (BLE)-enabled neural microsystem suitable for activity-dependent stimulation applications in non-human primate models. The resulting microsystem is fabricated in all-rigid and rigid-flex substrates, operates autonomously from a 3.6V, 1.6A.h., lithium-ion battery, weighs approximately 48 grams (including the battery), consumes ~618μW under nominal operation, and is housed within a custom 3D-printed resin enclosure. An end-to-end BLE-enabled wireless communication protocol is developed to allow the user to wirelessly program the ICMS ASIC, measure stimulation rate, estimate electrode site impedance, and measure system power supply levels from a user base station. Comprehensive bench-top and in vitro tests demonstrate successful operation of the implemented hardware, software, and firmware. Additionally, initial results from in vivo experiments in awake squirrel monkeys are reported.
Pedram Mohseni (Committee Chair)
Francis Merat (Committee Member)
Soumyajit Mandal (Committee Member)
Randolph Nudo (Committee Member)
95 p.
Electrical Engineering
Bluetooth Low Energy, activity-dependent stimulation, integrated systems, neural interfaces, wireless communication

Recommended Citations

Citations

  • Vitale, N. H. (2020). A Bluetooth Low Energy-Enabled Neural Microsystem for Activity-Dependent Intracortical Microstimulation in Non-Human Primates [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case156534949054962

    APA Style (7th edition)

  • Vitale, Nicholas. A Bluetooth Low Energy-Enabled Neural Microsystem for Activity-Dependent Intracortical Microstimulation in Non-Human Primates. 2020. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case156534949054962.

    MLA Style (8th edition)

  • Vitale, Nicholas. "A Bluetooth Low Energy-Enabled Neural Microsystem for Activity-Dependent Intracortical Microstimulation in Non-Human Primates." Master's thesis, Case Western Reserve University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case156534949054962

    Chicago Manual of Style (17th edition)

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© 2019, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.