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Investigations of Anatomical Connectivity in the Internal Capsule of Macaques with Diffusion Magnetic Resonance Imaging

Taljan, Kyle Andrew Ignatius
http://rave.ohiolink.edu/etdc/view?acc_num=csu1311093061

Abstract Details

2011, Master of Science in Biomedical Engineering, Cleveland State University, Fenn College of Engineering.
Understanding anatomical connectivity is crucial for improving outcomes of deep brain stimulation surgery. Tractography is a promising method for noninvasively investigating anatomical connectivity, but connections between subcortical regions have not been closely examined by this method. As many connections to subcortical regions converge at the internal capsule (IC), we investigate the connectivity through the IC to three subcortical nuclei (caudate, lentiform nucleus, and thalamus) in 6 macaques. We show that a statistical correction for a known distance-related artifact in tractography results in large changes in connectivity patterns. Our results suggest that care should be taken in using tractography to assess anatomical connectivity between subcortical structures.
Cameron McIntyre, PhD (Committee Chair)
Ken Sakaie, PhD (Advisor)
Nolan Holland, PhD (Committee Member)
39 p.
Biomedical Engineering
MRI; deep brain stimulation; diffusion; statistical correction; tractography; internal capsule; subcortical

Recommended Citations

Citations

  • Taljan, K. A. I. (2011). Investigations of Anatomical Connectivity in the Internal Capsule of Macaques with Diffusion Magnetic Resonance Imaging [Master's thesis, Cleveland State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=csu1311093061

    APA Style (7th edition)

  • Taljan, Kyle. Investigations of Anatomical Connectivity in the Internal Capsule of Macaques with Diffusion Magnetic Resonance Imaging. 2011. Cleveland State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=csu1311093061.

    MLA Style (8th edition)

  • Taljan, Kyle. "Investigations of Anatomical Connectivity in the Internal Capsule of Macaques with Diffusion Magnetic Resonance Imaging." Master's thesis, Cleveland State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=csu1311093061

    Chicago Manual of Style (17th edition)

csu1311093061
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© 2011, all rights reserved.
This open access ETD is published by Cleveland State University and OhioLINK.