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Determining the influence of limb and gender on blood pressure regulation and functional sympatholysis during the application of negative pressure

Pollock, Brandon S
http://rave.ohiolink.edu/etdc/view?acc_num=kent1445348894

Abstract Details

2015, PHD, Kent State University, College of Education, Health and Human Services / School of Health Sciences.
Lower body negative pressure (LBNP), which unloads cardiopulmonary and arterial baroreceptors, is a widely used method for studying various cardiovascular responses to hemorrhaging and orthostatic stress. The purposes of this investigation were to validate the use of LBNP as a research technique for studying the human cardiovascular responses to hemorrhaging and to use LBNP in combination with a dynamic handgrip exercise protocol to determine if gender differences exist in functional sympatholysis. Twenty healthy college-aged male (N = 10) and female (N = 10) participants visited the exercise science laboratory on one occasion. For the first part, participant’s whole left arm, whole left leg, and a portion of their left leg volume-matched to their whole arm was subject to two stages of negative pressure (-30 mmHg and -60 mmHg) lasting 5 minutes each. For the second part, participants performed 3 minute stages of dynamic handgrip exercise at 15%, 30%, and 45% of their max voluntary contraction, with one minute rest intervals taken between each stage, then repeated this protocol again while subject to -30 mmHg LBNP. Responses in heart rate, stroke volume, mean arterial pressure, brachial blood flow, brachial diameter, and forearm muscle oxygenation were continuously recorded. There were minimal differences observed in the cardiovascular responses to negative pressure when applied to the upper body versus when applied to the lower body, and there were no significant gender differences in response to LBNP at rest or during exercise.
John McDaniel (Advisor)
J. Derek Kingsley (Committee Member)
Angela Ridgel (Committee Member)
John Gunstad (Committee Member)
125 p.
Physiology
functional sympatholysis; cardiovascular; gender; lower; upper; negative pressure; LBNP; UBNP

Recommended Citations

Citations

  • Pollock, B. S. (2015). Determining the influence of limb and gender on blood pressure regulation and functional sympatholysis during the application of negative pressure [Doctoral dissertation, Kent State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=kent1445348894

    APA Style (7th edition)

  • Pollock, Brandon. Determining the influence of limb and gender on blood pressure regulation and functional sympatholysis during the application of negative pressure. 2015. Kent State University, Doctoral dissertation. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=kent1445348894.

    MLA Style (8th edition)

  • Pollock, Brandon. "Determining the influence of limb and gender on blood pressure regulation and functional sympatholysis during the application of negative pressure." Doctoral dissertation, Kent State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=kent1445348894

    Chicago Manual of Style (17th edition)

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© 2015, all rights reserved.
This open access ETD is published by Kent State University and OhioLINK.