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Mary Saha (Halpin) Dissertation.pdf (5.03 MB)

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Evolutionary Trends in Viral Pathogens within and between Outbreaks

Saha, Mary E
http://rave.ohiolink.edu/etdc/view?acc_num=kent1511199228856908

Abstract Details

2017, PHD, Kent State University, College of Arts and Sciences / Department of Biological Sciences.
RNA viruses are a consistent challenge to public health, ranging from the consistent seasonal threat of influenza to less predictable outbreaks of more virulent pathogens like Ebolavirus. Due to their high mutation rate and lack of error correction, RNA viruses can rapidly evolve, creating challenges for long term treatment strategies and vaccines. This danger is amplified when paired with their ability to disperse, spreading worldwide quickly by taking advantage of the same means of travel as their human and animal hosts. Therefore, it is important to be able to follow and predict likely evolutionary changes of these viruses, particularly changes in the direction of increased pathogenicity and/or communicability. These evolutionary changes must be mapped both within an individual outbreak and between separately occurring outbreaks. This study used available sequence information to provide evolutionary insights into Influenza A and the Ebolavirus.
Helen Piontkivska (Advisor)
209 p.
Biology
Ebolavirus; evolution;

Recommended Citations

Citations

  • Saha, M. E. (2017). Evolutionary Trends in Viral Pathogens within and between Outbreaks [Doctoral dissertation, Kent State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=kent1511199228856908

    APA Style (7th edition)

  • Saha, Mary. Evolutionary Trends in Viral Pathogens within and between Outbreaks. 2017. Kent State University, Doctoral dissertation. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=kent1511199228856908.

    MLA Style (8th edition)

  • Saha, Mary. "Evolutionary Trends in Viral Pathogens within and between Outbreaks." Doctoral dissertation, Kent State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=kent1511199228856908

    Chicago Manual of Style (17th edition)

kent1511199228856908
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© 2017, all rights reserved.
This open access ETD is published by Kent State University and OhioLINK.