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Neural Mechanisms Underlying Stress-Induced Depression and Its Prevention

Nagabhushan, Sahana
http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1304462392

Abstract Details

2011, BS, Kent State University, College of Arts and Sciences / Department of Biological Sciences.
Psychological and physical stressors stimulate the noradrenergic system which results in the induction of cytokine production via norepinephrine acting on β-adrenergic receptors. These cytokines, especially IL-1β, and the dysregulation of the noradrenergic system are implicated in depressive behavior. Current antidepressants increase norepinephrine in the brain which often leads to worsening of depressive symptoms during early stages of treatment. Blocking the effects of norepinephrine, with a β-adrenergic receptor blocker like Propranolol, may prevent stress-induced depression.
John Johnson (Advisor)
Douglas Kline (Committee Member)
Bansidhar Datta (Committee Member)
Manfred van Dulmen (Committee Member)
Behavioral Sciences
depression; stress; norepinephrine; b-adrenergic receptors; propranolol; interleukin-1

Recommended Citations

Citations

  • Nagabhushan, S. (2011). Neural Mechanisms Underlying Stress-Induced Depression and Its Prevention [Undergraduate thesis, Kent State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1304462392

    APA Style (7th edition)

  • Nagabhushan, Sahana. Neural Mechanisms Underlying Stress-Induced Depression and Its Prevention. 2011. Kent State University, Undergraduate thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1304462392.

    MLA Style (8th edition)

  • Nagabhushan, Sahana. "Neural Mechanisms Underlying Stress-Induced Depression and Its Prevention." Undergraduate thesis, Kent State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1304462392

    Chicago Manual of Style (17th edition)

ksuhonors1304462392
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© 2011, all rights reserved.
This open access ETD is published by Kent State University Honors College and OhioLINK.