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Potential mismatches in structural and functional organization in the gracile nucleus

Niranjan, Shalini S.
http://rave.ohiolink.edu/etdc/view?acc_num=mco1223921577

Abstract Details

2008, Master of Science in Biomedical Sciences (MSBS), University of Toledo, College of Graduate Studies.
The gracile nucleus (GN) is a major brainstem processing center for somatosensory inputs. GN neurons often have functional receptive fields (RFs) on the toes, but there is little consensus on how these RFs are related to primary sensory inputs from toes. This project compared structural overlap in GN terminations of afferents from different toes, and numbers of toes in GN functional RFs. The results suggest that structural convergence of afferent terminations from at least 3-4 toes is common; in contrast, although some GN RFs reflected functional inputs from up to 4-5 toes, most RFs reflected inputs from 1-2 toes. These findings raise the possibility that structural convergence of sensory afferents from the toes is broader than the afferent convergence that is usually reflected in functional RFs. This type of potential mismatch has been previously described in somatosensory cortex and may partly explain rapid GN RF changes after disruptions of afferents.
John Wall, PhD (Committee Chair)
Nicolas Chiaia, PhD (Committee Member)
Richard Lane, PhD (Committee Member)
96 p.
Neurology
gracile nucleus; receptive fields; dorsal column nuclei; transganglionic transport; primary afferents

Recommended Citations

Citations

  • Niranjan, S. S. (2008). Potential mismatches in structural and functional organization in the gracile nucleus [Master's thesis, University of Toledo]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=mco1223921577

    APA Style (7th edition)

  • Niranjan, Shalini. Potential mismatches in structural and functional organization in the gracile nucleus. 2008. University of Toledo, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=mco1223921577.

    MLA Style (8th edition)

  • Niranjan, Shalini. "Potential mismatches in structural and functional organization in the gracile nucleus." Master's thesis, University of Toledo, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=mco1223921577

    Chicago Manual of Style (17th edition)

mco1223921577
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© 2008, all rights reserved.
This open access ETD is published by University of Toledo Health Science Campus and OhioLINK.