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A Comparative Analysis of Conventional MLC Based IMRT and Solid Compensator Based IMRT Treatment Techniques

Khadija, Murshed

Abstract Details

2009, Master of Science in Biomedical Sciences (MSBS), University of Toledo, College of Medicine.
Intensity Modulation Radiation Therapy (IMRT) using multi leaf collimation systems hasrevolutionized the delivery of radiation therapy. However, these treatments may result in delivery of very large monitor units (MUs) through very small fields where electronic equilibrium may be compromised. This also raises some concerns in terms of the scattered dose to areas outside the main treatment volume. The goals of this study were to evaluate the clinical differences of solid compensator and MLC based IMRT treatments. The investigation was extended to compare fluence maps at prescription plane, the delivery time, monitor unit requirements, and deposited dose to outside of the target volume. The ADAC Pinnacle inverse planning system was used to generate MLC based IMRT plans and using the .decimal software package, generating the compensator based IMRT plans. Treatment plans were generated for prostate, adrenal gland, brain, and head and neck cases. Delivery of treatment plans were performed on a Rando phantom and mosfet dosimeters, TLDs, and films were used to compare measured doses of MLC and solid IMRT treatments. For the more complex plans the solid compensators resulted in 26.7% fewer monitor units and delivery time was reduce in half when compared with mlc plans. However for relatively simple IMRT plans such as prostate boosts or adrenal gland plans where the target has a relatively simple cylindrical shape the mlc plans resulted in an average of 41.6% fewer MUs and required about 16% less time to deliver than the solid compensator plans. Mosfet skin dose analysis showed that the solid compensators resulted in an average of 17.5% less dose. Film analysis also showed that Compensator plans delivered less out of field fluence. Based on the results it is evident that solid compensators are a viable IMRT treatment option when considering complex target arrangements that require many beams segments. For relatively simple plans which result in fewer and larger beam segments compensator based plans showed no advantage over mlc plans in regards to MUs and treatment time.
E. Ishmael Parsai, Ph.D. (Committee Chair)
Diana Shvydka, Ph.D. (Committee Member)
John Feldmeier, D.O. (Committee Member)
44 p.

Recommended Citations

Citations

  • Khadija, M. (2009). A Comparative Analysis of Conventional MLC Based IMRT and Solid Compensator Based IMRT Treatment Techniques [Master's thesis, University of Toledo]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=mco1264434257

    APA Style (7th edition)

  • Khadija, Murshed. A Comparative Analysis of Conventional MLC Based IMRT and Solid Compensator Based IMRT Treatment Techniques. 2009. University of Toledo, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=mco1264434257.

    MLA Style (8th edition)

  • Khadija, Murshed. "A Comparative Analysis of Conventional MLC Based IMRT and Solid Compensator Based IMRT Treatment Techniques." Master's thesis, University of Toledo, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=mco1264434257

    Chicago Manual of Style (17th edition)