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Yates_ConesThesis_Final.pdf (3.65 MB)

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Retrospective Dosimetric Comparison of MLC Defined Conformal Arc to Stereotactic Cone Plans for Single Fraction SRS on the Varian Edge (TM)

Yates, Justin, Yates
http://orcid.org/0000-0001-5121-0794
http://rave.ohiolink.edu/etdc/view?acc_num=mco1525441068022458

Abstract Details

2018, Master of Science in Biomedical Sciences (MSBS), University of Toledo, Biomedical Sciences (Medical Physics: Radiation Oncology).
The University of Toledo currently uses the 2.5mm MLC leaves on our Varian Edge (Varian Medical Systems Inc., Palo Alto, CA) for every SRS case. For most cases the MLCs provide excellent results. However, their unanimous use in the clinic leads to question if they are superior to cones for every case. For small single fraction cases, it may be possible that better plans can be achieved with the use of SRS cones. It is this topic which we investigate in a retrospective study which is a continuation of previous work done here at the University of Toledo. Varian stereotactic cones are commissioned in Raystation6 (RaySearch Laboratories, Stockholm, Sweden). Patients with small (<2.8cc) single fraction SRS targets are re-planned with the Varian cones and compared to the original MLC defined plans using the RTOG conformity index, Paddick conformity index, Conformity Gradient index, Gradient index, Dose Gradient index, and an in-house gradient index. Target volumes are also evaluated for the minimum spherical volume required to circumscribe them. This spherical index is compared with the gradient and conformity indices to investigate a potential correlation. New treatment plans are created using Raystation6 and Varian SRS cones. The plans show steeper dose fall-off can be achieved with stereotactic cones compared to MLCs. The plans showed no significant difference in dose conformity to the target volume between the modalities or any correlation of conformity to the shape of the target.
David Pearson, PhD (Advisor)
47 p.
Oncology; Radiation
Stereotactic; Cones; Varian Edge; SRS; Conformity; Dose Gradient; W1 Scintillator; commissioning; commissioning cones; radiation therapy; Edge Diode

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Citations

  • Yates, Yates, J. (2018). Retrospective Dosimetric Comparison of MLC Defined Conformal Arc to Stereotactic Cone Plans for Single Fraction SRS on the Varian Edge (TM) [Master's thesis, University of Toledo]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=mco1525441068022458

    APA Style (7th edition)

  • Yates, Yates, Justin. Retrospective Dosimetric Comparison of MLC Defined Conformal Arc to Stereotactic Cone Plans for Single Fraction SRS on the Varian Edge (TM). 2018. University of Toledo, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=mco1525441068022458.

    MLA Style (8th edition)

  • Yates, Yates, Justin. "Retrospective Dosimetric Comparison of MLC Defined Conformal Arc to Stereotactic Cone Plans for Single Fraction SRS on the Varian Edge (TM)." Master's thesis, University of Toledo, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=mco1525441068022458

    Chicago Manual of Style (17th edition)

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This open access ETD is published by University of Toledo Health Science Campus and OhioLINK.