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A Patient Specific Treatment Planning Method for BNCT Utilizing MCNP and RayStation

Seekamp, James M

Abstract Details

2020, Master of Science in Biomedical Sciences (MSBS), University of Toledo, Biomedical Sciences (Medical Physics: Radiation Oncology).
Current boron neutron capture therapy (BNCT) treatment planning systems compute dose is several different ways. Many of these systems have chosen Monte Carlo N-Particle (MCNP) as their dose engine due to its widespread usage and verified results. Several of the MCNP based treatment planning systems use standard DICOM computed tomography (CT) files to voxelize and create the patient specific model in MCNP. From this point on boron concentrations must be assigned by tissue type. All bone in the model has the same boron concentration, all healthy tissue will be set to one concentration, and the target volume will be set to a different spatially homogeneous concentration. This work seeks to address these assumptions about boron concentration by also integrating positron emission tomography (PET) information into the model so that each voxel in the model has the correct boron concentration. This step improves the accuracy of the patient specific model which improves the accuracy of dose calculations. that this method is creating a patient specific model with non-homogeneous boron concentration and that the calculated dose distribution is reasonable. This method was also developed to use RayStation as its visual display interface to visualize doses, volumes, and dose volume histograms due its ease of use.
Nicholas Sperling (Committee Chair)
Ishmael Parsai (Committee Member)
Diana Shvydka (Committee Member)
56 p.

Recommended Citations

Citations

  • Seekamp, J. M. (2020). A Patient Specific Treatment Planning Method for BNCT Utilizing MCNP and RayStation [Master's thesis, University of Toledo]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=mco1588797752065809

    APA Style (7th edition)

  • Seekamp, James. A Patient Specific Treatment Planning Method for BNCT Utilizing MCNP and RayStation. 2020. University of Toledo, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=mco1588797752065809.

    MLA Style (8th edition)

  • Seekamp, James. "A Patient Specific Treatment Planning Method for BNCT Utilizing MCNP and RayStation." Master's thesis, University of Toledo, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=mco1588797752065809

    Chicago Manual of Style (17th edition)