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miami1154451707.pdf (603.19 KB)
ETD Abstract Container
Abstract Header
Tannins as Anti-inflammatory Agents
Author Info
Jeffers, Melanie Diane
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=miami1154451707
Abstract Details
Year and Degree
2006, Master of Science, Miami University, Chemistry and Biochemistry.
Abstract
The potential of dietary and herbal polyphenols to act as beneficial antioxidants or anti-inflammatory agents, or as harmful pro-oxidants, is a topic of intense current interest. The first half of this research involved using SDS-PAGE gels to elucidate tannin-protein complexation. The second half of this study attempts to evaluate the anti-inflammatory or pro-inflammatory activity of the tannin pentagalloyl glucose within an ex vivo model system using peripheral blood mononuclear cells from rabbit. The oxidative burst from cells stimulated with phorbol ester was monitored with cytochrome c. The results provide preliminary data that supports the hypothesis that tannins such as pentagalloyl glucose minimize the inflammatory response.
Committee
Ann Hagerman (Advisor)
Pages
79 p.
Subject Headings
Chemistry, Biochemistry
Keywords
Tannins
;
Polyphenolics
;
Reactive oxygen species
;
Anti-inflammatory
;
Monocytes
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Citations
Jeffers, M. D. (2006).
Tannins as Anti-inflammatory Agents
[Master's thesis, Miami University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=miami1154451707
APA Style (7th edition)
Jeffers, Melanie.
Tannins as Anti-inflammatory Agents.
2006. Miami University, Master's thesis.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=miami1154451707.
MLA Style (8th edition)
Jeffers, Melanie. "Tannins as Anti-inflammatory Agents." Master's thesis, Miami University, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=miami1154451707
Chicago Manual of Style (17th edition)
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Document number:
miami1154451707
Download Count:
8,704
Copyright Info
© 2006, all rights reserved.
This open access ETD is published by Miami University and OhioLINK.