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miami1251845808.pdf (2.77 MB)
ETD Abstract Container
Abstract Header
Concept Lattice Analysis for Annotation Objects
Author Info
Yi, Wenting
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=miami1251845808
Abstract Details
Year and Degree
2009, Master of Computer Science, Miami University, Computer Science and Systems Analysis.
Abstract
The Gene Ontology (GO) provides a terminology to describe biological concepts and their relationships in a consistent and species-independent manner. Recent research has begun exploring the use of formal concept analysis (FCA) on annotated biological objects such as genes and gene products to discover the similarity and relationships among them. This thesis has produced a generic FCA software tool that creates a variety of concept lattices and incorporates the structure of the ontological terminology used for annotations. The user can tailor the creation of the concept lattices based on characteristics of the annotations and view a 3D visualization of the results. Numerous querying capabilities for exploring the resulting concept lattices are also included. Real-world data including a breast-cancer gene list from the University of Cincinnati's Childrens' Hospital and Medical Center and a well-known set of gene products GPD194 from the research literature are used to evaluate the FCA software.
Committee
Valerie Cross, PhD (Advisor)
Alton Sanders, PhD (Committee Member)
Michael Zmuda, PhD (Committee Member)
Pages
137 p.
Subject Headings
Computer Science
Keywords
gene ontology
;
concept lattice analysis
;
concept lattice similarity
;
concept approximatioin
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Citations
Yi, W. (2009).
Concept Lattice Analysis for Annotation Objects
[Master's thesis, Miami University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=miami1251845808
APA Style (7th edition)
Yi, Wenting.
Concept Lattice Analysis for Annotation Objects.
2009. Miami University, Master's thesis.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=miami1251845808.
MLA Style (8th edition)
Yi, Wenting. "Concept Lattice Analysis for Annotation Objects." Master's thesis, Miami University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=miami1251845808
Chicago Manual of Style (17th edition)
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Document number:
miami1251845808
Download Count:
597
Copyright Info
© 2009, all rights reserved.
This open access ETD is published by Miami University and OhioLINK.