Skip to Main Content
 

Global Search Box

 
 
 
 

Files

File List


miami1281297277.pdf (1.6 MB)

ETD Abstract Container

Abstract Header

Changes in adult rat superior cervical ganglion following axotomy

Morris, Teresa Ann
http://rave.ohiolink.edu/etdc/view?acc_num=miami1281297277

Abstract Details

2010, Master of Science, Miami University, Zoology.
The infiltration of immune cells into the superior cervical ganglion (SCG) following axotomy was characterized in the present study over short- and long-term survival times. OX-42, ED1, ED2, and Iba1 were used to label monocytes and macrophages associated with the SCG. Though immune cells infiltrated the SCG and associated with neuronal cell bodies, there was no evidence of apoptosis at any time point examined. These findings led to the hypothesis that the infiltration served a neuroprotective role at early time points following axotomy to promote cell survival and facilitate regeneration. However, assessment of tyrosine hydroxylase in the SCG and its target, the pineal gland, revealed only a slight recovery from the injury. We conclude that the immune cell infiltration served to promote cell survival in the SCG at early time points. However, regeneration of SCG axons apparently proceeds slowly, with little recovery at the late time points.
Lori Isaacson, PhD (Advisor)
Michael Robinson, PhD (Committee Member)
Katia Del Rio-Tsonis, PhD (Committee Member)
70 p.
Biology; Zoology
superior cervical ganglion; axotomy; immune; regeneration

Recommended Citations

Citations

  • Morris, T. A. (2010). Changes in adult rat superior cervical ganglion following axotomy [Master's thesis, Miami University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=miami1281297277

    APA Style (7th edition)

  • Morris, Teresa. Changes in adult rat superior cervical ganglion following axotomy. 2010. Miami University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=miami1281297277.

    MLA Style (8th edition)

  • Morris, Teresa. "Changes in adult rat superior cervical ganglion following axotomy." Master's thesis, Miami University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=miami1281297277

    Chicago Manual of Style (17th edition)

miami1281297277
291
© 2010, all rights reserved.
This open access ETD is published by Miami University and OhioLINK.