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Effects of Prior Aerobic Exercise on Vascular Dysfunction Induced by Prolonged Sitting in Healthy Men

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2017, Master of Science in Exercise and Health Studies, Miami University, Exercise and Health Studies.
Prolonged sitting has been shown to impair vascular endothelial function (VEF) in healthy men. Conversely, acute aerobic exercise improves VEF. PURPOSE: The objective of this study was to examine whether acute aerobic exercise would prevent impairments in VEF during sitting. METHODS: Eleven healthy men [21.2 ± 0.6 y (mean ± SE)] participated in two randomized 3-hour sitting trials preceded by a single bout of treadmill exercise (45 min at 65% maximal oxygen consumption (VO2max)) (EX) or 45 min of rest (REST). Superficial femoral artery flow-mediated dilation (FMD) was assessed after an overnight fast (Pre), 1-hour following EX (or REST) (Post), and at 1-hour intervals during a 3-hour uninterrupted sitting challenge. Two-way repeated-measures ANOVA and Bonferroni post-hoc tests were used to evaluate differences within and between groups. RESULTS: In the REST trial, femoral artery FMD declined from Pre (2.6 ± 0.5%) at 1, 2, and 3 hours of sitting (P<0.05) and resting shear rate decreased at 3 hours (P<0.05). Femoral artery FMD (2.7 ± 0.6%) and resting shear rate responses were unaffected (P=0.09) when sitting was preceded by EX. CONCLUSION: A single bout of aerobic exercise prevents the decline in FMD induced by 3-hours of uninterrupted sitting in healthy men.
Kevin Ballard (Committee Chair)
Kyle Timmerman (Committee Member)
Rose Marie Ward (Committee Member)
71 p.

Recommended Citations

Citations

  • Duguid, R. M. (2017). Effects of Prior Aerobic Exercise on Vascular Dysfunction Induced by Prolonged Sitting in Healthy Men [Master's thesis, Miami University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=miami1493035630069766

    APA Style (7th edition)

  • Duguid, Robert. Effects of Prior Aerobic Exercise on Vascular Dysfunction Induced by Prolonged Sitting in Healthy Men. 2017. Miami University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=miami1493035630069766.

    MLA Style (8th edition)

  • Duguid, Robert. "Effects of Prior Aerobic Exercise on Vascular Dysfunction Induced by Prolonged Sitting in Healthy Men." Master's thesis, Miami University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=miami1493035630069766

    Chicago Manual of Style (17th edition)