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MASTERS THESIS FINAL DRAFT.pdf (407.97 KB)

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Associations Among Age, Physical Activity, Insulin Sensitivity, Resistin, Endothelin-1, Adiponectin, and IGF-1 Levels

Thomas, Caitlyn Alyse
http://orcid.org/0000-0001-9115-7350
http://rave.ohiolink.edu/etdc/view?acc_num=miami1532976274272611

Abstract Details

2018, Master of Science in Exercise and Health Studies, Miami University, Exercise and Health Studies.
A variety of cytokines, including resistin, adiponectin, endothelin-1 (ET-1) and insulin-like growth factor-1 (IGF-1), are thought to influence adipose and endothelial tissue function. The PURPOSE of this study was to assess the relationships among age, physical activity level, insulin sensitivity and resistin, adiponectin, ET-1 and IGF-1 levels in healthy young and older adults. METHODS: A sample of 20 young (age: 21.0±1.2y) and 20 older (age: 68.4±4.0y) adults was used. The following were assessed: habitual physical activity level (PA); body composition; and fasting serum levels of resistin, adiponectin, ET-1, IGF-1, glucose and insulin. The homeostatic model assessment of insulin resistance (HOMA-IR) was calculated. RESULTS: PA level was not correlated with any protein, glucose or insulin levels. There were no significant differences in resistin and adiponectin levels between young and old subjects (p = 0.056; p = 0.81). There were significant differences in ET-1 and IGF-1 levels between young and old subjects (p= 0.01; p= 2.15 x 10-7). Adiponectin and IGF-1 were inversely correlated with BMI (p = 0.004; p= 0.002). HOMA-IR was positively correlated with BF% (p = 0.015). CONCLUSIONS: Resistin, adiponectin, ET-1, IGF-1 and PA levels do not appear to be predictive of insulin sensitivity in young or older adults.
Kyle Timmerman, Dr. (Committee Chair)
Kevin Ballard, Dr. (Committee Member)
Michael Crowder, Dr. (Committee Member)
36 p.
Kinesiology
Resistin; Physical Activity; Insulin Sensitivity; Age

Recommended Citations

Citations

  • Thomas, C. A. (2018). Associations Among Age, Physical Activity, Insulin Sensitivity, Resistin, Endothelin-1, Adiponectin, and IGF-1 Levels [Master's thesis, Miami University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=miami1532976274272611

    APA Style (7th edition)

  • Thomas, Caitlyn . Associations Among Age, Physical Activity, Insulin Sensitivity, Resistin, Endothelin-1, Adiponectin, and IGF-1 Levels . 2018. Miami University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=miami1532976274272611.

    MLA Style (8th edition)

  • Thomas, Caitlyn . "Associations Among Age, Physical Activity, Insulin Sensitivity, Resistin, Endothelin-1, Adiponectin, and IGF-1 Levels ." Master's thesis, Miami University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=miami1532976274272611

    Chicago Manual of Style (17th edition)

miami1532976274272611
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© 2018, all rights reserved.
This open access ETD is published by Miami University and OhioLINK.