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Associations Between Physical Activity Level and Adiponectin/Leptin Ratios in Older Adults

McMath, Arden Lee
http://orcid.org/0000-0002-7288-2511
http://rave.ohiolink.edu/etdc/view?acc_num=miami1556816283317575

Abstract Details

2019, Master of Science in Exercise and Health Studies, Miami University, Exercise and Health Studies.
The ratio of adiponectin-to-leptin (A/L) is strongly correlated with risk of chronic disease19, 29, 36. Limited research has been conducted examining the relationship between physical activity and A/L. Thus, the PURPOSES of this study are to evaluate the associations between A/L and habitual physical activity, metabolic syndrome criteria (MSF), and HOMA-IR. METHODS: The proposed project examined the relationship between adiponectin and leptin with habitual physical activity levels and HOMA – IR in healthy adults (age: 58 years or older). Habitual physical activity data were obtained objectively (7-day accelerometry; OPA) and subjectively (CHAMPS; SPA). Serum hormone levels was measured through ELISA of blood samples. Partial correlations and hierarchical linear regression analyses were also performed. RESULTS: A/L and adiponectin were directly, while leptin was indirectly associated with SPA, except when adjustment for BMI was performed. Leptin was also indirectly associated with OPA prior to BMI adjustment. A/L was predictive of HOMA-IR and MSF, although leptin and adiponectin included separately in a model predicted greater variance. CONCLUSION: Our results supported all hypotheses, although it appears that leptin has the strongest relationship with measures of physical activity and the hormones added as separate entities in a model are more predictive of HOMA-IR and MSF compared to A/L.
Kyle Timmerman, Dr. (Advisor)
Kevin Ballard, Dr. (Committee Member)
Ronald Cox, Dr. (Committee Member)
34 p.
Behavioral Sciences; Biology; Health; Health Care; Health Sciences; Kinesiology; Physiology
adiponectin-leptin ratio; adiponectin; leptin; physical activity and older adults; adiponectin-leptin and metabolic syndrome; adiponecitn-leptin and insulin sensitivity; adiponectin-leptin and physical activity; adipocytokines; hormones and exercise

Recommended Citations

Citations

  • McMath, A. L. (2019). Associations Between Physical Activity Level and Adiponectin/Leptin Ratios in Older Adults [Master's thesis, Miami University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=miami1556816283317575

    APA Style (7th edition)

  • McMath, Arden. Associations Between Physical Activity Level and Adiponectin/Leptin Ratios in Older Adults. 2019. Miami University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=miami1556816283317575.

    MLA Style (8th edition)

  • McMath, Arden. "Associations Between Physical Activity Level and Adiponectin/Leptin Ratios in Older Adults." Master's thesis, Miami University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=miami1556816283317575

    Chicago Manual of Style (17th edition)

miami1556816283317575
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© 2019, all rights reserved.
This open access ETD is published by Miami University and OhioLINK.