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ISIAD_thesis_v1.pdf (3.1 MB)

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Estimating Optical Properties of Liquid Phantoms with Multiple Correction Methods Using Measurements from a Single Integrating Sphere and the Inverse Adding-Double Algorithm

Vinoin Devpaul, Vincely
http://orcid.org/0000-0003-4844-5984
http://rave.ohiolink.edu/etdc/view?acc_num=miami1595973167641113

Abstract Details

2020, Master of Science, Miami University, Physics.
Integrating spheres (IS) are regarded as the gold-standard method to measure total reflectance and transmittance. These measurements combined with the high-speed solver, the inverse adding-doubling (IAD) method, provide efficient estimations of optical properties (absorption and reduced scattering) from thin unknown turbid samples. In this thesis, the performance of a table-top IS/IAD method to calculate optical properties will be explored using a robust set of optical phantoms whose properties mimic typical biological tissues. An analysis of the limitations of the system revealed light losses in IS measurements that translate to errors in inverse calculations. A robust Monte-Carlo model mimicking light propagation under the experimental configuration, is developed with simulations indicating relative errors in measurements up to 25%. Two commonly used correction methodologies, an experimental (substitution) and a theoretical (IAD-MC) correction protocol, were implemented to improve system performance. The effectiveness of these correction methodologies for multiple source configurations over a range of optical properties typical to biological media, was explored. These studies indicated that the theoretical correction along with a well collimated illumination source provide most accurate estimations of absorption and reduced scattering values by the IS/IAD method to within 0.05 cm−1 and 0.8 cm−1, respectively.
Karthik Vishwanath (Advisor)
Samir Bali (Committee Member)
Imran Mirza (Committee Member)
96 p.
Physics

Recommended Citations

Citations

  • Vinoin Devpaul, V. (2020). Estimating Optical Properties of Liquid Phantoms with Multiple Correction Methods Using Measurements from a Single Integrating Sphere and the Inverse Adding-Double Algorithm [Master's thesis, Miami University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=miami1595973167641113

    APA Style (7th edition)

  • Vinoin Devpaul, Vincely. Estimating Optical Properties of Liquid Phantoms with Multiple Correction Methods Using Measurements from a Single Integrating Sphere and the Inverse Adding-Double Algorithm . 2020. Miami University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=miami1595973167641113.

    MLA Style (8th edition)

  • Vinoin Devpaul, Vincely. "Estimating Optical Properties of Liquid Phantoms with Multiple Correction Methods Using Measurements from a Single Integrating Sphere and the Inverse Adding-Double Algorithm ." Master's thesis, Miami University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=miami1595973167641113

    Chicago Manual of Style (17th edition)

miami1595973167641113
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© 2020, all rights reserved.
This open access ETD is published by Miami University and OhioLINK.