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Lewis,_Kristin_accepted__Dissertation_10-07-14_FA_14.pdf (796.27 KB)
ETD Abstract Container
Abstract Header
Pain Modulation in Tension-Type and Migraine Headaches: The Offset Analgesia Effect
Author Info
Lewis, Kristin N.
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1412688879
Abstract Details
Year and Degree
2014, Doctor of Philosophy (PhD), Ohio University, Clinical Psychology (Arts and Sciences).
Abstract
Objective: Migraine and Tension-type headaches are common and disabling disorders, but their pathophysiologies are poorly understood. Dysfunctional pain inhibition is postulated to contribute to the development and/or maintenance of these disorders. Offset analgesia, a temporal contrast effect which activates brain structures involved in pain modulation, has never been assessed in headache sufferers. The object of the study was to compare the offset analgesia effect in a group of headache sufferers to a group of healthy controls. Methods: Undergraduate college students (N=111) were recruited through a research participant pool, and were compensated for their participation with research credit. Participants provided demographic and inclusion/exclusion information, and completed a diagnostic interview for headache disorders. Next, participants established their pain threshold for a temperature stimulus. This temperature was used in the offset analgesia procedure in which participants were asked to continuously rate a series of 3 temperatures: 5 seconds at pain threshold, 5 seconds at 1 degree Celsius above pain threshold, and 15 seconds at pain threshold. Results: Participants with headaches reported an average of 41 headaches a year, with the most common diagnosis being Frequent Episodic Tension-type (30%), followed by Migraine (26%), Infrequent Episodic Tension-type (9%), and Mixed (7%). Although offset analgesia was observed, t (99) = 3.54, p < .01, there was no significant difference in the degree of offset analgesia when healthy controls were compared to those with migraine or tension-type headache, F (2, 88) = 1.17, p = .31. Degree of offset analgesia also did not differ as a function of headache frequency, r < 0.04, n=76, p=.96. Conclusions: The current study demonstrated offset analgesia in a sample of young adults, and provides the first evidence that this form of pain modulation is not associated with headache symptoms. It should be noted, however, that differences may yet be observed in a clinical population with more severe and/or prolonged headache history.
Committee
Christopher France, PhD (Committee Chair)
Pages
75 p.
Subject Headings
Health
;
Psychology
Keywords
headache
;
pain modulation
;
offset analagesia
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Citations
Lewis, K. N. (2014).
Pain Modulation in Tension-Type and Migraine Headaches: The Offset Analgesia Effect
[Doctoral dissertation, Ohio University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1412688879
APA Style (7th edition)
Lewis, Kristin.
Pain Modulation in Tension-Type and Migraine Headaches: The Offset Analgesia Effect.
2014. Ohio University, Doctoral dissertation.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1412688879.
MLA Style (8th edition)
Lewis, Kristin. "Pain Modulation in Tension-Type and Migraine Headaches: The Offset Analgesia Effect." Doctoral dissertation, Ohio University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1412688879
Chicago Manual of Style (17th edition)
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Document number:
ohiou1412688879
Download Count:
776
Copyright Info
© 2014, all rights reserved.
This open access ETD is published by Ohio University and OhioLINK.