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osu1089949841.pdf (4.53 MB)
ETD Abstract Container
Abstract Header
Magnetic resonance imaging at ultra high field: implications for human neuroimaging
Author Info
Burgess, Richard Ely
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=osu1089949841
Abstract Details
Year and Degree
2004, Doctor of Philosophy, Ohio State University, Biomedical Engineering.
Abstract
Even before the development of magnetic resonance imaging, scientists and engineers repeatedly predicted that, despite the theoretical potential of high field, physical and engineering challenges would prevent the practical realization of gains in signal to noise. Many of the arguments used to disparage high field MRI can be divided into issues of uniform excitation, image distortion, and patient safety. In the former category lies challenges such as RF penetration limitations, dielectric resonances, coil self-resonance, coil-sample interactions, and RF power requirements, which may prevent uniform B1 can best be studied with numerical modeling techniques. Within the second category are effects such as chemical shift artifact, susceptibility distortions, and contrast convergence that can be well studied through analytic techniques and methodical manipulation of imaging parameters. In the category of safety belong RF power deposition and magnetohydrodynamic effects. In this thesis, issues of static field safety will be exhaustively explored and investigation of image contrast and quality will be undertaken to assess the potential of the 8 Tesla system for human neuroimaging. This thesis will specifically examine the theoretical risk of cardiac arrhythmia from induced currents and demonstrate the negligible cardiac, cognitive, and physiological bioeffects through animal and human studies. The extent of signal to noise ratio enhancement possible at 8 Tesla will be assessed and harnessed to obtain high resolution whole brain images. In the end, experimental results and analysis show that, despite the presence of artifact, high resolution images of the human brain with unique contrast can be safely obtained at 8 Tesla.
Committee
Pierre-Marie Robitaille (Advisor)
Pages
237 p.
Keywords
magnetic resonance
;
magnetic resonance imaging
;
MRI
;
high field
;
8 tesla
;
high resolution
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Citations
Burgess, R. E. (2004).
Magnetic resonance imaging at ultra high field: implications for human neuroimaging
[Doctoral dissertation, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1089949841
APA Style (7th edition)
Burgess, Richard.
Magnetic resonance imaging at ultra high field: implications for human neuroimaging.
2004. Ohio State University, Doctoral dissertation.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=osu1089949841.
MLA Style (8th edition)
Burgess, Richard. "Magnetic resonance imaging at ultra high field: implications for human neuroimaging." Doctoral dissertation, Ohio State University, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=osu1089949841
Chicago Manual of Style (17th edition)
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Document number:
osu1089949841
Download Count:
1,954
Copyright Info
© 2004, all rights reserved.
This open access ETD is published by The Ohio State University and OhioLINK.