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osu1196275397.pdf (164.4 KB)
ETD Abstract Container
Abstract Header
A new efficient model to investigate propofol injection pain
Author Info
Pappas, Eleni Elias
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=osu1196275397
Abstract Details
Year and Degree
2007, Master of Science, Ohio State University, Allied Medical Professions.
Abstract
Pain associated with the injection of propofol has been investigated in many studies. Our investigative model used a double-blinded construction that allowed the participant to act as the subject for both the test and control group. The subjects received simultaneous injections, one in each hand, through a 22 g IV catheter connected to a standard IV set-up placed in the dorsum of each hand. Together, 2 mL of propofol were injected in one hand and 2 mL of the propofol mixture containing 1mg/mL lidocaine or 0.02 mg remifentanil in the other hand. In this manner we were able to obtain adequate statistical power for this clinical study with a small number of subjects. Two groups of twenty-five subjects used this model to assess and compare discomfort experienced following the intravenous injection of plain propofol and either a mixture of propofol with lidocaine or propofol with remifentanil.
Committee
Guillermo Chacon (Advisor)
Pages
36 p.
Keywords
lidocaine
;
remifentanil
;
propofol
;
injection pain
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Citations
Pappas, E. E. (2007).
A new efficient model to investigate propofol injection pain
[Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1196275397
APA Style (7th edition)
Pappas, Eleni.
A new efficient model to investigate propofol injection pain.
2007. Ohio State University, Master's thesis.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=osu1196275397.
MLA Style (8th edition)
Pappas, Eleni. "A new efficient model to investigate propofol injection pain." Master's thesis, Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=osu1196275397
Chicago Manual of Style (17th edition)
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Document number:
osu1196275397
Download Count:
957
Copyright Info
© 2007, all rights reserved.
This open access ETD is published by The Ohio State University and OhioLINK.