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Fatigue of Polymers in the Roller Head Raceway of Extracorporeal Circuits

Bednarski Spiwak, Allison Joan
http://rave.ohiolink.edu/etdc/view?acc_num=osu1228329882

Abstract Details

2008, Doctor of Philosophy, Ohio State University, Biomedical Engineering.
Polyvinyl chloride (PVC) is a brittle amorphous polymer, but processing the PVC with plasticizer results in a flexible material able to form non-rigid tubing. Plasticized PVC (pPVC) is available in medical grade products for use in extracorporeal drug and fluid delivery. There are known complications including plasticizer loss, drug interactions, spallation and raceway rupture associated with this product when used in the roller pump of the cardiopulmonary bypass circuit.This is pioneering research that studies tubing fatigued by use in the roller head raceway. The hypothesis states pPVC tubing exposed to the roller head raceway in a system simulating cardiopulmonary bypass changes material properties for tensile strength, elastic modulus and elongation. An additional hypothesis states spallation is recognized continually during compression in the roller head raceway and occurs at multiple surfaces of the tubing inner lumen. Better evaluation of polymers approved and chosen for the specific medical application of extracorporeal circulation by the roller head raceway and other approved devices will be obtained through this research protocol. With this basic knowledge clinicians will better understand the product selections available and better understand how to evaluate material offered from the manufacturers for specific applications. Minimal research recognizes the basic science of spallation and catastrophic rupture that occur during cardiopulmonary bypass. Cardiopulmonary bypass material selection was made to alleviate these concerns including the switch to pPVC from other non-rigid polymers, such as silicone and natural rubber. PVC is known to have a complicated morphology unstable during the compression in the roller head raceway. The initial phase of the study will trend the change in mechanical behavior of the polymer tubing after exposure to fatigue stresses of cyclic bending and compression by the roller head contact. This includes mimicking set-up and priming techniques used to prepare the equipment for patient care. Physiological saline and lipid will be used to duplicate the blood interaction with the pPVC known to influence material chemical stability. Pump settings for occlusion and RPM will simulate clinical cardiopulmonary bypass protocols. The material takes on a more crystalline structure leading to changes in the performance of the pPVC material. This simulation will develop the knowledge to understand the changes in behavior experienced during a typical cardiac surgical procedure.
Derek Hansford, PhD (Advisor)
Alan Litsky, PhD (Committee Member)
Tom Williams, PhD (Committee Member)
137 p.
Engineering
plasticized poly(vinyl chloride); cardiopulmonary bypass; extracorporeal circulation; fatigue; roller head raceway

Recommended Citations

Citations

  • Bednarski Spiwak, A. J. (2008). Fatigue of Polymers in the Roller Head Raceway of Extracorporeal Circuits [Doctoral dissertation, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1228329882

    APA Style (7th edition)

  • Bednarski Spiwak, Allison. Fatigue of Polymers in the Roller Head Raceway of Extracorporeal Circuits. 2008. Ohio State University, Doctoral dissertation. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1228329882.

    MLA Style (8th edition)

  • Bednarski Spiwak, Allison. "Fatigue of Polymers in the Roller Head Raceway of Extracorporeal Circuits." Doctoral dissertation, Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1228329882

    Chicago Manual of Style (17th edition)

osu1228329882
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© 2008, all rights reserved.
This open access ETD is published by The Ohio State University and OhioLINK.