Skip to Main Content
 

Global Search Box

 
 
 
 

Files

File List


osu1248123054.pdf (487.46 KB)

ETD Abstract Container

Abstract Header

DEPRESSION AND TRAJECTORIES OF THE PHYSIOLOGICAL STRESS RESPONSE AFTER BREAST CANCER DIAGNOSIS

Wu, Salene M.
http://rave.ohiolink.edu/etdc/view?acc_num=osu1248123054

Abstract Details

2009, Master of Arts, Ohio State University, Psychology.
The current study used McEwen’s (1998) theory of allostatic load to investigate the relationship of depression to the stress hormones cortisol, adrenocorticotropic hormone (ACTH), epinephrine and norepinephrine in breast cancer patients. Stage II or III breast cancer patients (n=227) were assessed following surgery and prior to adjuvant treatment and at 4, 8, 12, 18 and 24 month follow-ups. Hierarchical linear modeling was used. Depression in the year one was negatively related to cortisol but positively related to greater increases of cortisol. Depression was related to greater decreases in epinephrine in the first year and negatively related to epinephrine in year two. Depression was not related to ACTH or norepinephrine. Results indicate blunting of physiological responding, McEwen’s (1998) fourth condition of allostatic load. Results suggest that effects of stress are not static.
Barbara Andersen, PhD (Committee Chair)
Daniel Strunk, PhD (Committee Member)
Julian Thayer, PhD (Committee Member)
99 p.
Psychology
depression; physiological stress response; breast cancer

Recommended Citations

Citations

  • Wu, S. M. (2009). DEPRESSION AND TRAJECTORIES OF THE PHYSIOLOGICAL STRESS RESPONSE AFTER BREAST CANCER DIAGNOSIS [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1248123054

    APA Style (7th edition)

  • Wu, Salene. DEPRESSION AND TRAJECTORIES OF THE PHYSIOLOGICAL STRESS RESPONSE AFTER BREAST CANCER DIAGNOSIS. 2009. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1248123054.

    MLA Style (8th edition)

  • Wu, Salene. "DEPRESSION AND TRAJECTORIES OF THE PHYSIOLOGICAL STRESS RESPONSE AFTER BREAST CANCER DIAGNOSIS." Master's thesis, Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1248123054

    Chicago Manual of Style (17th edition)

osu1248123054
438
© 2009, all rights reserved.
This open access ETD is published by The Ohio State University and OhioLINK.