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Nutrition-Related Disease Risk in Pediatric Cancer Survivors

Buegel, Angela Lila
http://rave.ohiolink.edu/etdc/view?acc_num=osu1250544679

Abstract Details

2009, Master of Science, Ohio State University, Allied Medicine.
The prevalence of overweight and obesity and other nutritionally related disease development among pediatric cancer survivors is well known to be above national norms. This is a retrospective cohort study designed to investigate the relationship between childhood cancer survivorship and nutritionally related disease development. The objective of this study was to gather data from existing pediatric cancer survivors in order to study disease development in relation to the type of cancer the patient had, the course of treatment, and to nutrition care that patient may have received. Seventy five subjects, with diagnoses of ALL, AML, Burkitt’s lymphoma, neuroblastoma, or Wilm’s tumor, 2 or more years into survivorship, and meeting the other stated criteria, were admitted to the study. Body mass index (BMI) was calculated for each subject using the most recent height and weight, and prevalence of overweight or obesity was established using the current CDC growth charts and guidelines. Of the 75 subjects in the study, 30 (40%) were found to be overweight or obese overall, with relatively equal distribution in those categories (16 overweight vs. 14 obese). When separating subjects into their respective diagnosis categories, the rate of overweight and obesity was higher than the overall number in all groups except the neuroblastoma group (ALL 42%, AML 57%, Burkitt’s 50%, Wilm’s 56% vs. Neuroblastoma 21%). Subject data was analyzed for development of nutritionally related diseases since diagnosis of cancer. Forty nine (65%) were found to have developed these types of diseases including overweight/obesity, osteoporosis, restrictive airway disease, hypothyroidism, hypertension, gallbladder disease, hypercholesterolemia, and anemia. When overweight and obesity were excluded, 20 subjects (27%) remained. Forty seven (63%) of the 75 total subjects in the study had some type of nutrition education, 45 (60%) received nutrition intervention, and 25 (33%) received nutrition support. In the overweight and obese group (30 subjects), 20 (67%) received nutrition education, 19 (63%) received nutrition intervention, and 8 (27%) received nutrition support. When the overweight and obese subject data was removed from the overall sample, 45 subjects remained and 27 (60%) were found to have received nutrition education, 26 (58%) had nutrition intervention, and 17 (38%) had nutrition support during or after treatment. The results of this study corroborate with the results of previous studies. The rates of overweight and obesity, along with other nutritionally related diseases, are high in this sample even though most subjects are 5 years post-therapy or less. The nutrition education and intervention provided to the overweight and obese group was slightly higher than those who were not in this category, possibly indicating that the timing and quality of nutrition care plays a role in prevention of disease. More research is needed in this area to delineate the appropriate quality and quantity of nutrition care in the prevention of late effects of cancer treatment.
Kay Wolf, PhD (Advisor)
Jill Clutter, PhD (Committee Member)
Laura Martin, MD (Committee Member)
63 p.
Health; Health Care; Nutrition
pediatric cancer survivor; cancer survivor; nutrition and cancer survivors; disease risk and cancer survivors; nutritionally related disease risk in cancer survivors

Recommended Citations

Citations

  • Buegel, A. L. (2009). Nutrition-Related Disease Risk in Pediatric Cancer Survivors [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1250544679

    APA Style (7th edition)

  • Buegel, Angela. Nutrition-Related Disease Risk in Pediatric Cancer Survivors. 2009. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1250544679.

    MLA Style (8th edition)

  • Buegel, Angela. "Nutrition-Related Disease Risk in Pediatric Cancer Survivors." Master's thesis, Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1250544679

    Chicago Manual of Style (17th edition)

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This open access ETD is published by The Ohio State University and OhioLINK.