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osu1308339910.pdf (4.36 MB)
ETD Abstract Container
Abstract Header
Transcriptional control of cell proliferation in Arabidopsis thaliana
Author Info
MAKKENA, SRILAKSHMI
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=osu1308339910
Abstract Details
Year and Degree
2011, Doctor of Philosophy, Ohio State University, Plant Cellular and Molecular Biology.
Abstract
Control of cell proliferation is essential for normal plant development and is controlled at many levels, including that of transcription. We have used the model plant species Arabidopsis thaliana to investigate control of cell proliferation during development by three transcription factors: SPATULA (SPT), encoding a bHLH transcription factor and FOUR LIPS (FLP) and its paralog MYB88, both encoding R2R3 MYB transcription factors. Detailed analysis of embryo and root development showed that loss of SPT function causes an increase in quiescent center size in both the embryonic and postembryonic stem cell niche. spt mutants exhibit other pleotropic developmental phenotypes, including longer hypocotyls, more flowers, shorter internodes and an extended flowering period. FOUR LIPS (FLP) and MYB88 have overlapping functions in restricting Guard Mother Cell (GMC) division during stomatal development. In our current study, we have identified another role for FLP during female gametogenesis.
Committee
Rebecca Lamb (Advisor)
Iris Meier (Committee Member)
Patrice Hamel (Committee Member)
JC Jang (Committee Member)
Pages
229 p.
Subject Headings
Plant Sciences
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Citations
MAKKENA, S. (2011).
Transcriptional control of cell proliferation in Arabidopsis thaliana
[Doctoral dissertation, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1308339910
APA Style (7th edition)
MAKKENA, SRILAKSHMI.
Transcriptional control of cell proliferation in Arabidopsis thaliana.
2011. Ohio State University, Doctoral dissertation.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=osu1308339910.
MLA Style (8th edition)
MAKKENA, SRILAKSHMI. "Transcriptional control of cell proliferation in Arabidopsis thaliana." Doctoral dissertation, Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1308339910
Chicago Manual of Style (17th edition)
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Document number:
osu1308339910
Download Count:
805
Copyright Info
© 2011, all rights reserved.
This open access ETD is published by The Ohio State University and OhioLINK.