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The Role of Tobacco Use in the Etiology of Acoustic Neuroma

Palmisano, Sadie Taylor

Abstract Details

2011, Master of Science, Ohio State University, Public Health.
Background: Two previous studies suggest that cigarette smoking reduces acoustic neuroma risk; however, an association between use of snuff tobacco and acoustic neuroma has not been previously investigated. Methods: The authors conducted a case control study in Sweden from 2002 to 2007, in which 451 cases and 710 population based controls completed questionnaires. Cases and controls were matched on gender, region, and age within five years. The authors estimated odds ratios using conditional logistic regression analyses, adjusted for education and tobacco use (snuff use in the smoking analysis, and smoking in the snuff analysis). Results: Risk of acoustic neuroma was greatly reduced in male current smokers (odds ratio [OR]=0.41, 95% confidence interval [CI]: 0.23-0.74), and moderately reduced in female current smokers (OR=0.70, 95% CI: 0.40-1.23). In contrast, current snuff use among males was not associated with risk of acoustic neuroma (OR=0.94, 95% CI: 0.57-1.55). Conclusions: The authors’ findings are consistent with previous reports of lower acoustic neuroma risk among current cigarette smokers than among never smokers. The absence of an association between snuff use and acoustic neuroma suggests that some constituent of tobacco smoke other than nicotine may confer protection against acoustic neuroma.
Judith Schwartzbaum, PhD (Committee Chair)
Randall Harris, MD, PhD (Committee Member)
30 p.

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Citations

  • Palmisano, S. T. (2011). The Role of Tobacco Use in the Etiology of Acoustic Neuroma [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1312908629

    APA Style (7th edition)

  • Palmisano, Sadie. The Role of Tobacco Use in the Etiology of Acoustic Neuroma. 2011. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1312908629.

    MLA Style (8th edition)

  • Palmisano, Sadie. "The Role of Tobacco Use in the Etiology of Acoustic Neuroma." Master's thesis, Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1312908629

    Chicago Manual of Style (17th edition)