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osu1312908629.pdf (1.02 MB)
ETD Abstract Container
Abstract Header
The Role of Tobacco Use in the Etiology of Acoustic Neuroma
Author Info
Palmisano, Sadie Taylor
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=osu1312908629
Abstract Details
Year and Degree
2011, Master of Science, Ohio State University, Public Health.
Abstract
Background: Two previous studies suggest that cigarette smoking reduces acoustic neuroma risk; however, an association between use of snuff tobacco and acoustic neuroma has not been previously investigated. Methods: The authors conducted a case control study in Sweden from 2002 to 2007, in which 451 cases and 710 population based controls completed questionnaires. Cases and controls were matched on gender, region, and age within five years. The authors estimated odds ratios using conditional logistic regression analyses, adjusted for education and tobacco use (snuff use in the smoking analysis, and smoking in the snuff analysis). Results: Risk of acoustic neuroma was greatly reduced in male current smokers (odds ratio [OR]=0.41, 95% confidence interval [CI]: 0.23-0.74), and moderately reduced in female current smokers (OR=0.70, 95% CI: 0.40-1.23). In contrast, current snuff use among males was not associated with risk of acoustic neuroma (OR=0.94, 95% CI: 0.57-1.55). Conclusions: The authors’ findings are consistent with previous reports of lower acoustic neuroma risk among current cigarette smokers than among never smokers. The absence of an association between snuff use and acoustic neuroma suggests that some constituent of tobacco smoke other than nicotine may confer protection against acoustic neuroma.
Committee
Judith Schwartzbaum, PhD (Committee Chair)
Randall Harris, MD, PhD (Committee Member)
Pages
30 p.
Subject Headings
Public Health
Keywords
acoustic neuroma
;
vestibular schwannoma
;
tobacco
;
cigarette smoking
;
snuff
;
snus
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Citations
Palmisano, S. T. (2011).
The Role of Tobacco Use in the Etiology of Acoustic Neuroma
[Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1312908629
APA Style (7th edition)
Palmisano, Sadie.
The Role of Tobacco Use in the Etiology of Acoustic Neuroma.
2011. Ohio State University, Master's thesis.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=osu1312908629.
MLA Style (8th edition)
Palmisano, Sadie. "The Role of Tobacco Use in the Etiology of Acoustic Neuroma." Master's thesis, Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1312908629
Chicago Manual of Style (17th edition)
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Document number:
osu1312908629
Download Count:
477
Copyright Info
© 2011, all rights reserved.
This open access ETD is published by The Ohio State University and OhioLINK.