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Correlation Between AC/A Ratio and Ciliary Muscle Morphology in School-Age Children

Fadel, Haind Mosbah Noraden, MD

Abstract Details

2011, Master of Science, Ohio State University, Vision Science.
Purpose: To examine how the morphology of the ciliary muscle varies as a function of AC/A ratio and to investigate the difference between the thickness of the ciliary muscle during accommodation and during cycloplegia. Methods: Measurements were performed on the right eye only of thirty children aged 6 to 12 years. Height and weight were measured. Accommodative response was measured by autorefraction through habitual correction. Axial length was measured with the IOLMaster. Temporal ciliary muscle images from anterior segment Vistante OCT at 1mm (CMT1), 2mm (CMT2), and 3mm (CMT3) posterior to the scleral spur at 0D and 4D stimulus levels and under cycloplegia were measured four times each. Accommodative response and pupil size data were simultaneously recorded by the PowerRefractor during ciliary muscle measurements. Result: There were no significant correlations between AC/A ratio and the changes in ciliary muscle thicknesses, CMT1 (P= 0.8), CMT2 (P= 0.8), CMT3 (P=0.9), or CMT MAX (P=0.9). Axial length has an inverse correlation with the changes in ciliary muscle thicknesses at CMT1 (P=0.004), CMT2 (P=0.04), and CMT MAX (P= 0.03), but not with CMT3 (P= 0.07). However, when the extreme changes in CMT measures were removed, there was not a significant correlation with axial length at any location. Age was not significantly correlated with changes in CMT1 (P=0.18), CMT2 (P=0.4), CMT3 (P=0.5), or CMT MAX (P= 0.4). Conclusions: The AC/A ratio did not appear to be significantly correlated with the changes in ciliary muscle thicknesses with accommodation in this study. Increased axial length was correlated with thinning of the ciliary muscle, possibly due to the positive correlation between axial length and ciliary muscle thickness. Further investigation is necessary to determine whether the association truly exists and the potential reason for the relationship.
Melissa Bailey, OD, PhD (Advisor)
Jeffrey Walline, OD, PhD (Advisor)
Lisa Jones-Jordan, PhD (Committee Member)
52 p.

Recommended Citations

Citations

  • Fadel, MD, H. M. N. (2011). Correlation Between AC/A Ratio and Ciliary Muscle Morphology in School-Age Children [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1322590123

    APA Style (7th edition)

  • Fadel, MD, Haind. Correlation Between AC/A Ratio and Ciliary Muscle Morphology in School-Age Children. 2011. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1322590123.

    MLA Style (8th edition)

  • Fadel, MD, Haind. "Correlation Between AC/A Ratio and Ciliary Muscle Morphology in School-Age Children." Master's thesis, Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1322590123

    Chicago Manual of Style (17th edition)