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Validation and Repeatability of Pediatric Refractive Error Profile 2 (PREP2)

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2013, Master of Science, Ohio State University, Vision Science.
Many myopia control studies use refractive correction as a means to slow axial growth. The Pediatric Refractive Error Profile (PREP) is a survey used to measure quality of life of children wearing refractive correction and can be used in these studies. The PREP2 is an updated version of this survey. The purpose of this study is to compare the repeatability and validity of the PREP2 to the PREP. This was done by having subjects take two administrations of the each survey, separated by a week. On the initial visit, the parents also completed a survey of how they believed their child felt about his or her vision correction. Each survey was scored and the repeatability was established using Student’s t-test, 95% limits of agreement, Bland- Altman mean versus difference plots, and Pearson’s Correlation Coefficient. The validity was established by comparing correlation to the parent survey with Pearson’s Correlation Coefficient and comparing internal consistency within scales. We examined 25 glasses wearers and 20 contact lens wearers between the ages of eight and 14. There was no significant bias between the two administrations of the PREP or PREP2 on any scale except on the PREP Academics scale for glasses wearers (p=0.002). The limits of agreement of glasses wearers for the PREP ranged from ±26.5 to ±57.7, contact lens wearers for the PREP ranged from ±16.1 to ±34.7, glasses wearers for the PREP2 ranged from ±20.0 to ±33.8, and contact lens wearers for the PREP2 ranged from ±15.2 to ±25.3. Using Pearson’s Correlation Coefficient, all scales of the PREP and PREP2 were statistically significant with the exception of Near Vision of PREP for spectacle wearers (p=0.166). The correlation to the parent’s survey was statistically significant for Handling (p=<0.001) for the PREP and Overall Vision (p=<0.001), Appearance (p=0.001), and Activities (p=0.001) for the PREP2. The internal consistency was greater than 0.70 for Overall Vision, Appearance, Distance Vision, and Academics for the PREP and on all scales for the PREP2. The PREP2 has higher repeatability and validity than the PREP and is a better survey for following quality of life changes over time. Further studies need to be conducted to eliminate questions from each scale, determine the scalability via Rasch analysis, and validate the PREP2 in subjects wearing orthokeratology lenses.
Jeffrey J. Walline, OD, PhD (Advisor)
Dean VanNasdale, OD, PhD (Committee Member)
Katherine Osborn Lorenz, OD, MS (Committee Member)
87 p.

Recommended Citations

Citations

  • Andersen, C. E. (2013). Validation and Repeatability of Pediatric Refractive Error Profile 2 (PREP2) [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1363117173

    APA Style (7th edition)

  • Andersen, Courtney. Validation and Repeatability of Pediatric Refractive Error Profile 2 (PREP2). 2013. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1363117173.

    MLA Style (8th edition)

  • Andersen, Courtney. "Validation and Repeatability of Pediatric Refractive Error Profile 2 (PREP2)." Master's thesis, Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1363117173

    Chicago Manual of Style (17th edition)